Cellosaurus cell line (CVCL

Cellosaurus (CVCL_VR53)

Synonyms

CuFi3; Cystic Fibrosis, University of Iowa-3

Accession

CVCL_C458

Comments

Karyotypic information: 48,XY,+5,+20 [10] (PubMed=12676769).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.

Sequence variations

Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Heterozygous (PubMed=12676769).
Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Arg553Ter (c.1657C>T); ClinVar=VCV000007122; Zygosity=Heterozygous (PubMed=12676769).

Disease

Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

15Y

Category

Transformed cell line

STR profile

Source(s): ATCC=CRL-4014

Markers:

Amelogenin	X,Y
CSF1PO	10,13
D5S818	11,12
D7S820	10,11
D13S317	11,12
D16S539	12,13
TH01	9,9.3
TPOX	10,11
vWA	16,19

Publications

Hans Bennich, Stig Gunnar Olof Johansson, Jan Ponten;
Established immunoglobulin producing myeloma (IgE) and lymphoblastoid (IgG) cell lines from an IgE myeloma patient.
Clin. Exp. Immunol. 7:477-489(1970)

Do you know the sex of your cells?
Am. J. Physiol. Cell Physiol. 306:C3-C18(2014)

Cross-references

Cell line collections (Providers)

ATCC; CRL-4014 - Discontinued
CancerTools; 154446

Biological sample resources

BioSample; SAMN03471723

Encyclopedic resources

Wikidata; Q54814856

Entry history

Entry creation

22-Oct-2012

Last entry update

14-Aug-2025

Version number