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Cellosaurus CV-hIPS-B-control APP edition clone B11 (CVCL_VR51)

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Cell line name CV-hIPS-B-control APP edition clone B11
Synonyms GM25430-control APP edition clone B11; B11
Accession CVCL_VR51
Resource Identification Initiative To cite this cell line use: CV-hIPS-B-control APP edition clone B11 (RRID:CVCL_VR51)
Comments Population: Caucasian.
Characteristics: Control cell line for the APP-edited cell lines derived from CV-hIPS-B. Have been transfected with CAS9, guide RNA and APP repair oligo but have not been edited.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1N86 (CV-hIPS-B)
Sex of cell Male
Age at sampling 62Y
Category Induced pluripotent stem cell
Publications

PubMed=30686764; DOI=10.1016/j.stem.2018.12.013; PMCID=PMC6414424
Rik van der Kant, Vanessa F. Langness, Cheryl M. Herrera, Daniel A. Williams, Lauren K. Fong, Yves Leestemaker, Evelyne Steenvoorden, Kevin D. Rynearson, Jos F. Brouwers, J. Bernd Helms, Huib Ovaa ...Show all 15 authors... , Martin Giera, Steven L. Wagner, Anne G. Bang, Lawrence Steven B. Goldstein; Show fewer authors
Cholesterol metabolism is a druggable axis that independently regulates Tau and amyloid-beta in iPSC-derived Alzheimer's disease neurons.
Cell Stem Cell 24:363-375.e9(2019)

Cross-references
Encyclopedic resources Wikidata; Q93460588
Entry history
Entry creation13-Nov-2018
Last entry update30-Jan-2024
Version number8