ID   CV-hIPS-B-control APP edition clone B11
AC   CVCL_VR51
SY   GM25430-control APP edition clone B11; B11
DR   Wikidata; Q93460588
RX   PubMed=30686764;
CC   Population: Caucasian.
CC   Characteristics: Control cell line for the APP-edited cell lines derived from CV-hIPS-B. Have been transfected with CAS9, guide RNA and APP repair oligo but have not been edited.
CC   Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1N86 ! CV-hIPS-B
SX   Male
AG   62Y
CA   Induced pluripotent stem cell
DT   Created: 13-11-18; Last updated: 30-01-24; Version: 8
//
RX   PubMed=30686764; DOI=10.1016/j.stem.2018.12.013; PMCID=PMC6414424;
RA   van der Kant R., Langness V.F., Herrera C.M., Williams D.A.,
RA   Fong L.K., Leestemaker Y., Steenvoorden E., Rynearson K.D.,
RA   Brouwers J.F., Helms J.B., Ovaa H., Giera M., Wagner S.L., Bang A.G.,
RA   Goldstein L.S.B.;
RT   "Cholesterol metabolism is a druggable axis that independently
RT   regulates Tau and amyloid-beta in iPSC-derived Alzheimer's disease
RT   neurons.";
RL   Cell Stem Cell 24:363-375.e9(2019).
//