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Cellosaurus CV-hIPS-B-control APP KO clone 151 (CVCL_UI49)

[Text version]
Cell line name CV-hIPS-B-control APP KO clone 151
Synonyms GM25430-control APP KO clone 151; 151
Accession CVCL_UI49
Resource Identification Initiative To cite this cell line use: CV-hIPS-B-control APP KO clone 151 (RRID:CVCL_UI49)
Comments Population: Caucasian.
Characteristics: Control cell line for the APP KO cell line derived from CV-hIPS-B. Have been transfected with CAS9 and guide RNA but have not been edited.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1N86 (CV-hIPS-B)
Sex of cell Male
Age at sampling 62Y
Category Induced pluripotent stem cell
Publications

PubMed=30686764; DOI=10.1016/j.stem.2018.12.013; PMCID=PMC6414424
van der Kant R., Langness V.F., Herrera C.M., Williams D.A., Fong L.K., Leestemaker Y., Steenvoorden E., Rynearson K.D., Brouwers J.F., Helms J.B., Ovaa H., Giera M., Wagner S.L., Bang A.G., Goldstein L.S.B.
Cholesterol metabolism is a druggable axis that independently regulates Tau and amyloid-beta in iPSC-derived Alzheimer's disease neurons.
Cell Stem Cell 24:363-375.e9(2019)

Cross-references
Encyclopedic resources Wikidata; Q93460589
Entry history
Entry creation25-Feb-2019
Last entry update30-Jan-2024
Version number7