• Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gln149Ter (c.445C>T); ClinVar=VCV000404164; Zygosity=Homozygous (PubMed=17088437; Cosmic-CLP=905947; DepMap=ACH-000649).
  
• Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=31068700).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; c.560-2A>G; ClinVar=VCV003148158; Zygosity=Heterozygous; Note=Splice acceptor mutation (Cosmic-CLP=905947; DepMap=ACH-000649).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro278Ala (c.832C>G); ClinVar=VCV000376645; Zygosity=Heterozygous (PubMed=9331090; Cosmic-CLP=905947; DepMap=ACH-000649).
  
• Mutation; HGNC; HGNC:12687; VHL; Simple; p.Gly104Alafs*55 (c.311delG); Zygosity=Homozygous (PubMed=7915601; PubMed=17088437; Cosmic-CLP=905947; DepMap=ACH-000649).
  

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PubMed=22068913; DOI=10.1073/pnas.1111840108; PMCID=PMC3219108
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PubMed=22185343; DOI=10.1186/1471-2407-11-523; PMCID=PMC3292516
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PubMed=22347499; DOI=10.1371/journal.pone.0031628; PMCID=PMC3276511
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PubMed=22384151; DOI=10.1371/journal.pone.0032096; PMCID=PMC3285665
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
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PubMed=22628656; DOI=10.1126/science.1218595; PMCID=PMC3526189
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PubMed=22949125; DOI=10.1002/ijc.27822
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PubMed=23856246; DOI=10.1158/0008-5472.CAN-12-3342; PMCID=PMC4893961
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PubMed=23933261; DOI=10.1016/j.celrep.2013.07.018
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PubMed=24279929; DOI=10.1186/2049-3002-1-20; PMCID=PMC4178206
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PubMed=24670534; DOI=10.1371/journal.pone.0092047; PMCID=PMC3966786
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PubMed=25485619; DOI=10.1038/nbt.3080
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PubMed=25877200; DOI=10.1038/nature14397
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PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347
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PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
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PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008
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PubMed=27141528; DOI=10.1016/j.dib.2016.04.001; PMCID=PMC4838930
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PubMed=27377824; DOI=10.1038/sdata.2016.52; PMCID=PMC4932877
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PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
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A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=27807467; DOI=10.1186/s13100-016-0078-4; PMCID=PMC5087121
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PubMed=27993170; DOI=10.1186/s12943-016-0565-8; PMCID=PMC5168717
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PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
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PubMed=28489074; DOI=10.1038/ncomms15165; PMCID=PMC5436135
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Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
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PubMed=30260228; DOI=10.1021/acs.jproteome.8b00538
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PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
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PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
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Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31267758; DOI=10.2217/fon-2019-0067
Ines Nogueira, Francisca Dias, Mariana Morais, Ana Luysa Teixeira, Rui Medeiros;
Everolimus resistance in clear cell renal cell carcinoma: miRNA-101 and HIF-2alpha as molecular triggers?
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PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254
David Paul Nusinow, John Szpyt, Mahmoud Ghandi, Christopher M. Rose, E. Robert McDonald 3rd, Marian Kalocsay, Judit Jane-Valbuena, Ellen T. Gelfand, Devin K. Schweppe, Mark P. Jedrychowski, Javad Golji ...Show all 20 authors... , Dale A. Porter, Tomas Rejtar, Y. Karen Wang, Gregory V. Kryukov, Frank Stegmeier, Brian K. Erickson, Levi Alexander Garraway, William Raj Sellers, Steven P. Gygi; Show fewer authors
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
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PubMed=38861359; DOI=10.1158/0008-5472.CAN-23-3031; PMCID=PMC11292194
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HTS384 NCI60: the next phase of the NCI60 screen.
Cancer Res. 84:2403-2416(2024)