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Cellosaurus MC615 (CVCL_0410)

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Cell line name MC615
Accession CVCL_0410
Resource Identification Initiative To cite this cell line use: MC615 (RRID:CVCL_0410)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryonic limb, cartilage; UBERON=UBERON_0010881.
Cell type: Chondrocyte; CL=CL_0000138.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: CD-1.
Hierarchy Children:
CVCL_H341 (MC615 4B5)CVCL_H342 (MC615 4C1)CVCL_H343 (MC615 4C3)
CVCL_H344 (MC615 4C6)CVCL_H345 (MC615 4C9)CVCL_H346 (MC615 4D5)
CVCL_H347 (MC615 4D7)CVCL_H348 (MC615 4E3)CVCL_H349 (MC615 4F6)
CVCL_H350 (MC615 4G11)CVCL_H351 (MC615 4H4)CVCL_H352 (MC615 5A2)
CVCL_H353 (MC615 5F12)CVCL_H354 (MC615 5F9)
Sex of cell Sex unspecified
Age at sampling 14FD
Category Transformed cell line
Publications

PubMed=7682698; DOI=10.1073/pnas.90.8.3289; PMCID=PMC46285
Frederic Mallein-Gerin, Bjorn Reno Olsen;
Expression of simian virus 40 large T (tumor) oncogene in mouse chondrocytes induces cell proliferation without loss of the differentiated phenotype.
Proc. Natl. Acad. Sci. U.S.A. 90:3289-3293(1993)

PubMed=16222708; DOI=10.1002/jcp.20511
Valentina Ulivi, Giorgia Tutolo, Frederic Mallein-Gerin, Antonio Daga, Ranieri Cancedda, Fiorella Descalzi Cancedda;
A common pathway in differentiation and inflammation: p38 mediates expression of the acute phase SIP24 iron binding lipocalin in chondrocytes.
J. Cell. Physiol. 206:728-737(2006)

PubMed=19670270; DOI=10.1002/jcb.22290
Cordula Surmann-Schmitt, Nathalie Widmann, Frederic Mallein-Gerin, Klaus von der Mark, Michael Stock;
Stable subclones of the chondrogenic murine cell line MC615 mimic distinct stages of chondrocyte differentiation.
J. Cell. Biochem. 108:589-599(2009)

Cross-references
Cell line databases/resources MCCL; MCC:0000304
Encyclopedic resources Wikidata; Q54904215
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14