ID   MC615
AC   CVCL_0410
DR   MCCL; MCC:0000304
DR   Wikidata; Q54904215
RX   PubMed=7682698;
RX   PubMed=16222708;
RX   PubMed=19670270;
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryonic limb, cartilage; UBERON=UBERON_0010881.
CC   Cell type: Chondrocyte; CL=CL_0000138.
CC   Breed/subspecies: CD-1.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   14FD
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 14
CH   CVCL_H341 ! MC615 4B5
CH   CVCL_H342 ! MC615 4C1
CH   CVCL_H343 ! MC615 4C3
CH   CVCL_H344 ! MC615 4C6
CH   CVCL_H345 ! MC615 4C9
CH   CVCL_H346 ! MC615 4D5
CH   CVCL_H347 ! MC615 4D7
CH   CVCL_H348 ! MC615 4E3
CH   CVCL_H349 ! MC615 4F6
CH   CVCL_H350 ! MC615 4G11
CH   CVCL_H351 ! MC615 4H4
CH   CVCL_H352 ! MC615 5A2
CH   CVCL_H353 ! MC615 5F12
CH   CVCL_H354 ! MC615 5F9
//
RX   PubMed=19670270; DOI=10.1002/jcb.22290;
RA   Surmann-Schmitt, Cordula
RA   Widmann, Nathalie
RA   Mallein-Gerin, Frederic
RA   von der Mark, Klaus
RA   Stock, Michael
RT   "Stable subclones of the chondrogenic murine cell line MC615 mimic
RT   distinct stages of chondrocyte differentiation.";
RL   J. Cell. Biochem. 108:589-599(2009).
//
RX   PubMed=7682698; DOI=10.1073/pnas.90.8.3289; PMCID=PMC46285;
RA   Mallein-Gerin, Frederic
RA   Olsen, Bjorn Reno
RT   "Expression of simian virus 40 large T (tumor) oncogene in mouse
RT   chondrocytes induces cell proliferation without loss of the
RT   differentiated phenotype.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:3289-3293(1993).
//
RX   PubMed=16222708; DOI=10.1002/jcp.20511;
RA   Ulivi, Valentina
RA   Tutolo, Giorgia
RA   Mallein-Gerin, Frederic
RA   Daga, Antonio
RA   Cancedda, Ranieri
RA   Cancedda, Fiorella Descalzi
RT   "A common pathway in differentiation and inflammation: p38 mediates
RT   expression of the acute phase SIP24 iron binding lipocalin in
RT   chondrocytes.";
RL   J. Cell. Physiol. 206:728-737(2006).
//