ID   MC615
AC   CVCL_0410
DR   MCCL; MCC:0000304
DR   Wikidata; Q54904215
RX   PubMed=7682698;
RX   PubMed=16222708;
RX   PubMed=19670270;
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryonic limb, cartilage; UBERON=UBERON_0010881.
CC   Cell type: Chondrocyte; CL=CL_0000138.
CC   Breed/subspecies: CD-1.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   14FD
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 13
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RX   PubMed=7682698; DOI=10.1073/pnas.90.8.3289; PMCID=PMC46285;
RA   Mallein-Gerin F., Olsen B.R.;
RT   "Expression of simian virus 40 large T (tumor) oncogene in mouse
RT   chondrocytes induces cell proliferation without loss of the
RT   differentiated phenotype.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:3289-3293(1993).
//
RX   PubMed=16222708; DOI=10.1002/jcp.20511;
RA   Ulivi V., Tutolo G., Mallein-Gerin F., Daga A., Cancedda R.,
RA   Cancedda F.D.;
RT   "A common pathway in differentiation and inflammation: p38 mediates
RT   expression of the acute phase SIP24 iron binding lipocalin in
RT   chondrocytes.";
RL   J. Cell. Physiol. 206:728-737(2006).
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RX   PubMed=19670270; DOI=10.1002/jcb.22290;
RA   Surmann-Schmitt C., Widmann N., Mallein-Gerin F., von der Mark K.,
RA   Stock M.;
RT   "Stable subclones of the chondrogenic murine cell line MC615 mimic
RT   distinct stages of chondrocyte differentiation.";
RL   J. Cell. Biochem. 108:589-599(2009).
//