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Cellosaurus A2780-1A9 (CVCL_H619)

[Text version]

Cell line name A2780-1A9
Synonyms A2780/1A9; A2780(1A9); 1A9
Accession CVCL_H619
Resource Identification Initiative To cite this cell line use: A2780-1A9 (RRID:CVCL_H619)
Comments Misspelling: IA9; Occasionally.
Derived from sampling site: Ovary.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
CVCL_B7S4 (1A9/CP10)CVCL_CZ93 (1A9/T80)CVCL_H620 (1A9PTX10)
CVCL_H622 (1A9PTX15)CVCL_H621 (1A9PTX22)CVCL_S476 (A2780-E(80))
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line

PubMed=1348364; DOI=10.1073/pnas.89.7.3070
Godwin A.K., Meister A., O'Dwyer P.J., Huang C.-S., Hamilton T.C., Anderson M.E.
High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.
Proc. Natl. Acad. Sci. U.S.A. 89:3070-3074(1992)

PubMed=16382445; DOI=10.1002/gcc.20300
Wang Y.C., Juric D., Francisco B., Yu R.X., Duran G.E., Chen G.K., Chen X., Sikic B.I.
Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines.
Genes Chromosomes Cancer 45:365-374(2006)

Chemistry resources ChEMBL-Cells; CHEMBL3307529
ChEMBL-Targets; CHEMBL614075
PubChem_Cell_line; CVCL_H619
Encyclopedic resources Wikidata; Q54582664
Gene expression databases GEO; GSM95437
Polymorphism and mutation databases Progenetix; CVCL_H619
Entry history
Entry creation11-Feb-2013
Last entry update15-Dec-2022
Version number19