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Cellosaurus 1A9/T80 (CVCL_CZ93)

[Text version]
Cell line name 1A9/T80
Synonyms 1A9 T80; 1A9T80
Accession CVCL_CZ93
Resource Identification Initiative To cite this cell line use: 1A9/T80 (RRID:CVCL_CZ93)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H619 (A2780-1A9)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=16382445; DOI=10.1002/gcc.20300
Wang Y.C., Juric D., Francisco B., Yu R.X., Duran G.E., Chen G.K., Chen X., Sikic B.I.
Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines.
Genes Chromosomes Cancer 45:365-374(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_CZ93
Encyclopedic resources Wikidata; Q54582666
Gene expression databases GEO; GSM95438
Polymorphism and mutation databases Progenetix; CVCL_CZ93
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number11