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Cellosaurus RIN-r (CVCL_D163)

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Cell line name RIN-r
Synonyms RINr
Accession CVCL_D163
Resource Identification Initiative To cite this cell line use: RIN-r (RRID:CVCL_D163)
Comments Characteristics: Established from the transplantable insulinoma RIN.
Characteristics: Secretes insulin and somatostatin (PubMed=6106192).
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Disease Rat insulinoma (NCIt: C121566)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS_0000603.
Hierarchy Children:
CVCL_U434 (RIN 1027-B2)CVCL_U435 (RIN 1046-38)CVCL_A7QF (RIN 1046-43)
CVCL_A7QE (RIN 1046-44)
Originate from same individual CVCL_0352 ! INS-1
CVCL_J993 ! INS-2
CVCL_3584 ! RIN-m
Sex of cell Male
Age at sampling 666D
Category Cancer cell line
Publications

PubMed=6106192; DOI=10.1073/pnas.77.6.3519; PMCID=PMC349648
Adi F. Gazdar, William L. Chick, Herbert Kazuto Oie, Harvie L. Sims, Dennis L. King, Gordon C. Weir, Vilma Lauris;
Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.
Proc. Natl. Acad. Sci. U.S.A. 77:3519-3523(1980)

PubMed=8697299
Vincent Poitout, Lawrence Karl Olson, R. Paul Robertson;
Insulin-secreting cell lines: classification, characteristics and potential applications.
Diabetes Metab. 22:7-14(1996)

PubMed=22538498; DOI=10.1159/000338793
Simona Grozinsky-Glasberg, Ilan Shimon, Hadara Rubinfeld;
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

Cross-references
Encyclopedic resources Wikidata; Q54950483
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number12