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Cellosaurus RIN 1027-B2 (CVCL_U434)

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Cell line name RIN 1027-B2
Synonyms RIN-1027-B2; RIN 1027 B2; Rin 1027-B2; RIN1027-B2; 1027-B2
Accession CVCL_U434
Resource Identification Initiative To cite this cell line use: RIN 1027-B2 (RRID:CVCL_U434)
Comments Characteristics: Secretes somatostatin (PubMed=2879852).
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Disease Rat insulinoma (NCIt: C121566)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS_0000603.
Hierarchy Parent: CVCL_D163 (RIN-r)
Children:
CVCL_U436 (RIN 1056A)
Sex of cell Male
Age at sampling 666D
Category Cancer cell line
Publications

PubMed=2879852; DOI=10.1172/JCI112819; PMCID=PMC424070
Jacques Philippe, William L. Chick, Joel Francis Habener;
Multipotential phenotypic expression of genes encoding peptide hormones in rat insulinoma cell lines.
J. Clin. Invest. 79:351-358(1987)

PubMed=10417352; DOI=10.1042/bj3410847; PMCID=PMC1220426
Carolyn Ewen Fiskerstrand, Paul Newey, Bahram Ebrahimi, Lesley Gerrard, Patrick Harrison, Gerard P. McGregor, John P. Quinn;
Novel cell lines for the analysis of preprotachykinin A gene expression identify a repressor domain 3' of the major transcriptional start site.
Biochem. J. 341:847-852(1999)

Cross-references
Encyclopedic resources Wikidata; Q54950467
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number12