• Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  
• Gene deletion; HGNC; 6770; SMAD4; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; 2514; CTNNB1; Simple; p.Ser33Phe (c.98C>T); ClinVar=VCV000017583; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; 8975; PIK3CA; Simple; p.Lys111Glu (c.331A>G); ClinVar=VCV000376482; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; 11103; SMARCB1; Simple; c.362+1G>C; ClinVar=VCV000582116; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
  

PubMed=1348862; DOI=10.1073/pnas.89.8.3498
Eijdems E.W.H.M., Borst P., Jongsma A.P.M., de Jong S., de Vries E.G.E., van Groenigen M., Versantvoort C.H.M., Nieuwint A.W.M., Baas F.
Genetic transfer of non-P-glycoprotein-mediated multidrug resistance (MDR) in somatic cell fusion: dissection of a compound MDR phenotype.
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PubMed=1353703
Nieuwint A.W.M., Baas F., Wiegant J., Joenje H.
Cytogenetic alterations associated with P-glycoprotein- and non-P-glycoprotein-mediated multidrug resistance in SW-1573 human lung tumor cell lines.
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PubMed=7809167; DOI=10.1073/pnas.91.26.13033
Muller M., Meijer C., Zaman G.J.R., Borst P., Scheper R.J., Mulder N.H., de Vries E.G.E., Jansen P.L.M.
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.
Proc. Natl. Acad. Sci. U.S.A. 91:13033-13037(1994)

PubMed=7644478; DOI=10.1073/pnas.92.17.7690
Zaman G.J.R., Lankelma J., van Tellingen O., Beijnen J.H., Dekker H., Paulusma C.C., Oude Elferink R.P.J., Baas F., Borst P.
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.
Proc. Natl. Acad. Sci. U.S.A. 92:7690-7694(1995)

PubMed=12093475; DOI=10.1016/S0006-2952(02)00983-8
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JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin.
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