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Cellosaurus MDCK2-ABCB1 (CVCL_A2JZ)

[Text version]
Cell line name MDCK2-ABCB1
Synonyms ABCB1-MDCK2; MDCK-hMDR1
Accession CVCL_A2JZ
Resource Identification Initiative To cite this cell line use: MDCK2-ABCB1 (RRID:CVCL_A2JZ)
Comments Transfected with: HGNC; 40; ABCB1.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Caution: There is another MDCK-II cell line with transfected human ABCB1: MDCK-MDR1 (Cellosaurus=CVCL_S586).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel.
Hierarchy Parent: CVCL_0424 (MDCK-II)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=25264565; DOI=10.1111/bcp.12522
Siegmund W., Modess C., Scheuch E., Methling K., Keiser M., Nassif A., Rosskopf D., Bednarski P.J., Borlak J., Terhaag B.
Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.
Br. J. Clin. Pharmacol. 79:501-513(2015)

Encyclopedic resources Wikidata; Q105510100
Entry history
Entry creation12-Jan-2021
Last entry update05-Oct-2023
Version number6