ID   MDCK2-ABCB1
AC   CVCL_A2JZ
SY   ABCB1-MDCK2; MDCK-hMDR1
DR   Wikidata; Q105510100
RX   PubMed=25264565;
CC   Genetic integration: Method=Transfection; Gene=HGNC; 40; ABCB1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Caution: There is another MDCK-II cell line with transfected human ABCB1: MDCK-MDR1 (Cellosaurus=CVCL_S586).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
CC   Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
HI   CVCL_0424 ! MDCK-II
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 12-01-21; Last updated: 10-09-24; Version: 7
//
RX   PubMed=25264565; DOI=10.1111/bcp.12522; PMCID=PMC4345960;
RA   Siegmund W., Modess C., Scheuch E., Methling K., Keiser M., Nassif A.,
RA   Rosskopf D., Bednarski P.J., Borlak J., Terhaag B.;
RT   "Metabolic activation and analgesic effect of flupirtine in healthy
RT   subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.";
RL   Br. J. Clin. Pharmacol. 79:501-513(2015).
//