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Cellosaurus CHO-S (CVCL_7183)

[Text version]
Cell line name CHO-S
Synonyms CHO-s; CHOS
Accession CVCL_7183
Resource Identification Initiative To cite this cell line use: CHO-S (RRID:CVCL_7183)
Comments Omics: Genomics; Whole genome sequencing.
Omics: Proteomics.
Omics: Transcriptomics; miRNA profiling; Microarray.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0213 (CHO)
Children:
CVCL_B6JC (C-HAlb)CVCL_A9NY (CHO C1s-/-)CVCL_VP59 (CHO MGAT1-)
CVCL_4386 (CHO-AA8)CVCL_D264 (CHO-AUXB1)CVCL_5A30 (CHO-AUXB3)
CVCL_M722 (CHO-AUXE29)CVCL_E5SM (CHO-S Cmah KO clone 1)CVCL_E5SN (CHO-S Cmah KO clone 25)
CVCL_E5SP (CHO-S Cmah KO clone 62)CVCL_WJ93 (CHO-S FUT8-/-)CVCL_A0AT (CHO-S r34.1 (clone D8))
CVCL_5A26 (CHO-S/C0101)CVCL_A0TS (CHO-S/H9C2)CVCL_XF07 (CHO-S/K70E10-1D6)
CVCL_E7G0 (CHO-SIINFEKL/H-2Kb)CVCL_0F81 (CHO-tsH1)CVCL_E3JG (CHOEBNALT85)
CVCL_E8IA (CHOS-X)CVCL_5J31 (ExpiCHO-S)CVCL_D604 (FreeStyle CHO-S)
CVCL_JG26 (hTf/CHO-S #17)CVCL_JG28 (hTf/CHO-S #29)CVCL_RN06 (PDIS-14)
CVCL_RN10 (PDIS-9)CVCL_EG61 (pREP4 cont/CHO-S #5)CVCL_A0AU (UCSC.PG128.CHO.S.F4)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-207.html
Provider; Thermo Fisher; A1155701; https://www.thermofisher.com/order/catalog/product/A1155701
Publications

PubMed=4585080; DOI=10.1016/S0091-679X(08)60052-7
Lawrence H. Thompson, Raymond M. Baker;
Isolation of mutants of cultured mammalian cells.
Methods Cell Biol. 6:209-281(1973)

PubMed=837451; DOI=10.1016/0092-8674(77)90224-0
Michael W. Konrad, Brian Storrie, Donald Arthur Glaser, Lawrence H. Thompson;
Clonal variation in colony morphology and growth of CHO cells cultured on agar.
Cell 10:305-312(1977)

DOI=10.3390/pr1030296
Florian Maria Wurm;
CHO quasispecies -- implications for manufacturing processes.
Processes 1:296-311(2013)

PubMed=23873082; DOI=10.1038/nbt.2624
Nathan E. Lewis, Xin Liu, Yu-Xiang Li, Harish Nagarajan, George Yerganian, Edward O'Brien, Aarash Bordbar, Anne M. Roth, Jeffrey Rosenbloom, Chao Bian, Min Xie ...Show all 21 authors... , Wen-Bin Chen, Ning Li, Deniz Baycin-Hizal, Haythem Latif, Jochen Forster, Michael J. Betenbaugh, Iman Famili, Xun Xu, Jun Wang, Bernhard Orn Palsson; Show fewer authors
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome.
Nat. Biotechnol. 31:759-765(2013)

PubMed=26993211; DOI=10.1016/j.jbiotec.2016.03.022
Gerald Klanert, Vaibhav Jadhav, Vinoth Shanmukam, Andreas Bernhard Diendorfer, Michael Karbiener, Marcel Scheideler, Juan Antonio Hernandez-Bort, Johannes Grillari, Matthias Hackl, Nicole Borth;
A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines.
J. Biotechnol. 235:150-161(2016)

DOI=10.3390/pr5020020
Florian Maria Wurm, Maria Joao Wurm;
Cloning of CHO cells, productivity and genetic stability -- a discussion.
Processes 5:20.1-20.13(2017)

PubMed=28876938; DOI=10.1021/acs.jproteome.7b00382
Kelley M. Heffner, Deniz Baycin-Hizal, George Yerganian, Amit Kumar, Ozge Can, Robert N. O'Meally, Robert Norman Cole, Raghothama Chaerkady, Herren Wu, Michael A. Bowen, Michael J. Betenbaugh;
Lessons from the hamster: Cricetulus griseus tissue and CHO cell line proteome comparison.
J. Proteome Res. 16:3672-3687(2017)

PubMed=32985598; DOI=10.1038/s41598-020-72959-8; PMCID=PMC7522264
Kelley M. Heffner, Deniz Baycin-Hizal, Natalia I. Majewska, Swetha Kumar, Venkata Gayatri Dhara, Jie Zhu, Michael A. Bowen, Diane Hatton, George Yerganian, Athena Yerganian, Robert N. O'Meally ...Show all 13 authors... , Robert Norman Cole, Michael J. Betenbaugh; Show fewer authors
Expanded Chinese hamster organ and cell line proteomics profiling reveals tissue-specific functionalities.
Sci. Rep. 10:15841.1-15841.12(2020)

PubMed=34050613; DOI=10.1002/biot.202100165
Maria Joao Wurm, Florian Maria Wurm;
Naming CHO cells for bio-manufacturing: genome plasticity and variant phenotypes of cell populations in bioreactors question the relevance of old names.
Biotechnol. J. 16:e2100165.1-e2100165.13(2021)

PubMed=36610518; DOI=10.1016/j.ymben.2022.12.009; PMCID=PMC11132536
Pavlos Kotidis, Roberto Donini, Johnny Arnsdorf, Anders Holmgaard Hansen, Bjorn Gunnar Rude Voldborg, Austin Wan-Tien Chiang, Stuart M. Haslam, Michael J. Betenbaugh, Ioscani Jimenez del Val, Nathan E. Lewis, Frederick J. Krambeck, Cleo Kontoravdi;
CHOGlycoNET: comprehensive glycosylation reaction network for CHO cells.
Metab. Eng. 76:87-96(2023)

Cross-references
Cell line databases/resources CLO; CLO_0037216
Lonza; 842
Encyclopedic resources Wikidata; Q54813102
Gene expression databases GEO; GSM1968575
GEO; GSM1968576
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23