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Cellosaurus CHO-S (CVCL_7183)

[Text version]

Cell line name CHO-S
Synonyms CHO-s; CHOS
Accession CVCL_7183
Resource Identification Initiative To cite this cell line use: CHO-S (RRID:CVCL_7183)
Comments Omics: Deep proteome analysis.
Omics: Genome sequenced.
Omics: miRNA expression profiling.
Derived from sampling site: Ovary.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0213 (CHO)
CVCL_M722 (CHO-AUXE29)CVCL_WJ93 (CHO-S FUT8-/-)CVCL_A0AT (CHO-S r34.1 (clone D8))
CVCL_5A26 (CHO-S/C0101)CVCL_A0TS (CHO-S/H9C2)CVCL_XF07 (CHO-S/K70E10-1D6)
CVCL_0F81 (CHO-tsH1)CVCL_Y012 (CHOS-XE)CVCL_5J31 (ExpiCHO-S)
CVCL_D604 (FreeStyle CHO-S)CVCL_JG26 (hTf/CHO-S #17)CVCL_JG28 (hTf/CHO-S #29)
CVCL_RN06 (PDIS-14)CVCL_RN10 (PDIS-9)CVCL_EG61 (pREP4 cont/CHO-S #5)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages https://www.thermofisher.com/order/catalog/product/A1155701

PubMed=4585080; DOI=10.1016/S0091-679X(08)60052-7
Thompson L.H., Baker R.M.
Isolation of mutants of cultured mammalian cells.
Methods Cell Biol. 6:209-281(1973)

PubMed=837451; DOI=10.1016/0092-8674(77)90224-0
Konrad M.W., Storrie B., Glaser D.A., Thompson L.H.
Clonal variation in colony morphology and growth of CHO cells cultured on agar.
Cell 10:305-312(1977)

Wurm F.M.
CHO quasispecies -- implications for manufacturing processes.
Processes 1:296-311(2013)

PubMed=23873082; DOI=10.1038/nbt.2624
Lewis N.E., Liu X., Li Y.-X., Nagarajan H., Yerganian G., O'Brien E., Bordbar A., Roth A.M., Rosenbloom J., Bian C., Xie M., Chen W.-B., Li N., Baycin-Hizal D., Latif H., Forster J., Betenbaugh M.J., Famili I., Xu X., Wang J., Palsson B.O.
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome.
Nat. Biotechnol. 31:759-765(2013)

PubMed=26993211; DOI=10.1016/j.jbiotec.2016.03.022
Klanert G., Jadhav V., Shanmukam V., Diendorfer A.B., Karbiener M., Scheideler M., Hernandez-Bort J.A., Grillari J., Hackl M., Borth N.
A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines.
J. Biotechnol. 235:150-161(2016)

Wurm F.M., Wurm M.J.
Cloning of CHO cells, productivity and genetic stability -- a discussion.
Processes 5:20.1-20.13(2017)

PubMed=28876938; DOI=10.1021/acs.jproteome.7b00382
Heffner K.M., Hizal D.B., Yerganian G., Kumar A., Can O., O'Meally R., Cole R., Chaerkady R., Wu H., Bowen M.A., Betenbaugh M.J.
Lessons from the hamster: Cricetulus griseus tissue and CHO cell line proteome comparison.
J. Proteome Res. 16:3672-3687(2017)

PubMed=32985598; DOI=10.1038/s41598-020-72959-8
Heffner K.M., Hizal D.B., Majewska N.I., Kumar S., Dhara V.G., Zhu J., Bowen M.A., Hatton D., Yerganian G., Yerganian A., O'Meally R., Cole R., Betenbaugh M.J.
Expanded Chinese hamster organ and cell line proteomics profiling reveals tissue-specific functionalities.
Sci. Rep. 10:15841-15841(2020)

PubMed=34050613; DOI=10.1002/biot.202100165
Wurm M.J., Wurm F.M.
Naming CHO cells for bio-manufacturing: genome plasticity and variant phenotypes of cell populations in bioreactors question the relevance of old names.
Biotechnol. J. 16:e2100165.1-e2100165.13(2021)

Cell line databases/resources CLO; CLO_0037216
Lonza; 842
Encyclopedic resources Wikidata; Q54813102
Gene expression databases GEO; GSM1968575
GEO; GSM1968576
Entry history
Entry creation04-Apr-2012
Last entry update15-Dec-2022
Version number19