• Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Pro (c.536A>C); ClinVar=VCV000376611; Zygosity=Heterozygous (PubMed=8790940).
  

PubMed=3972471; DOI=10.1002/ijc.2910350221
Masayoshi Namba, Koji Nishitani, Fuminori Hyodoh, Fujiko Fukushima, Tetsuo Kimoto;
Neoplastic transformation of human diploid fibroblasts (KMST-6) by treatment with 60Co gamma rays.
Int. J. Cancer 35:275-280(1985)

PubMed=2423124; DOI=10.1016/0304-419X(86)90001-6
Sidney E. Chang;
In vitro transformation of human epithelial cells.
Biochim. Biophys. Acta 823:161-194(1986)

PubMed=3140712
Masayoshi Namba, Koji Nishitani, Fujiko Fukushima, Tetsuo Kimoto;
Multistep carcinogenesis of normal human fibroblasts. Human fibroblasts immortalized by repeated treatment with Co-60 gamma rays were transformed into tumorigenic cells with Ha-ras oncogenes.
Anticancer Res. 8:947-958(1988)

PubMed=1537630; DOI=10.1002/ijc.2910500426
Koichiro Mihara, Li-Yan Bai, Yoshio Kano, Masahiro Miyazaki, Masayoshi Namba;
Malignant transformation of human fibroblasts previously immortalized with 60Co gamma rays.
Int. J. Cancer 50:639-643(1992)

DOI=10.11418/jtca1981.12.4_313
Masayoshi Namba, Li-Yan Bai, Yoshio Kano, Shigetaka Sugihara, Masahiro Miyazaki;
Multistep malignant transformation of human cells: immortalization of human fibroblasts by treatment with 60Co gamma rays and 4-nitroquinoline 1-oxide, and their malignant transformation with the ras oncogene.
Tissue Cult. Res. Commun. 12:313-318(1993)

PubMed=8105370; DOI=10.1128/mcb.13.10.6036-6043.1993; PMCID=PMC364663
Toshihiko Ogata, Dai Ayusawa, Masayoshi Namba, Eiichi Takahashi, Mitsuo Oshimura, Michio Oishi;
Chromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1.
Mol. Cell. Biol. 13:6036-6043(1993)

PubMed=8148305
Masayoshi Namba, Mikio Iijima, Tadashi Kondo, Israt Jahan, Koichiro Mihara;
Immortalization of normal human cells is a multistep process and a rate limiting step of neoplastic transformation of the cells.
Hum. Cell 6:253-259(1993)

PubMed=8557247; DOI=10.1007/BF00218823
Shinsuke Sugihara, Koichiro Mihara, Tohru Marunouchi, Hajime Inoue, Masayoshi Namba;
Telomere elongation observed in immortalized human fibroblasts by treatment with 60Co gamma rays or 4-nitroquinoline 1-oxide.
Hum. Genet. 97:1-6(1996)

PubMed=8790940; DOI=10.1247/csf.21.111
Koichiro Mihara, Mikio Iijima, Tadashi Kondo, Masayoshi Namba;
Selective expression of mutated p53 in human cells immortalized with either 4-nitroquinoline 1-oxide or 60Co gamma rays.
Cell Struct. Funct. 21:111-116(1996)

DOI=10.11418/jtca1981.16.3_173
Koichiro Mihara, Masahiro Miyazaki, Kazuo Fushimi, Toshiya Tsuji, Yusuke Inoue, Ken-ichi Fukaya, Ryuichiro Ohashi, Masayoshi Namba;
The p53 gene status and other cellular characteristics of human cell lines maintained in our laboratory.
Tissue Cult. Res. Commun. 16:173-178(1997)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=9359923; DOI=10.18926/AMO/30789
Koichiro Mihara, Masahiro Miyazaki, Tadashi Kondo, Kazuo Fushimi, Toshiya Tsuji, Yusuke Inoue, Ken-ichi Fukaya, Chikashi Ishioka, Masayoshi Namba;
Yeast functional assay of the p53 gene status in human cell lines maintained in our laboratory.
Acta Med. Okayama 51:261-265(1997)

CLPUB00712
Jeremy David Henson;
The role of alternative lengthening of telomeres in human cancer.
Thesis PhD (2006); University of Sydney; Sydney; Australia

PubMed=19935656; DOI=10.1038/nbt.1587
Jeremy David Henson, Ying Cao, Lily I. Huschtscha, Andy C.-M. Chang, Amy Y.M. Au, Hilda A. Pickett, Roger Robert Reddel;
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.
Nat. Biotechnol. 27:1181-1185(2009)