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Cellosaurus KMST-6/T (CVCL_2999)

[Text version]
Cell line name KMST-6/T
Accession CVCL_2999
Resource Identification Initiative To cite this cell line use: KMST-6/T (RRID:CVCL_2999)
Comments Population: Japanese.
Characteristics: Tumorigenic. Established from 2nd-passage tumors obtained in nude mice by transplanting one of the primary tumors produced by subcutaneous inoculation of KMST-6 cells into nude mice.
Doubling time: 37 +- 4.6 hours (Note=In 10% FBS), 47 +- 2.9 hours (Note=In 1% FBS) (PubMed=1537630).
Transformant: NCIt; C129640; Cobalt-60 gamma radiation.
Derived from site: In situ; Whole fetus; UBERON=UBERON_0000323.
Cell type: Fibroblast; CL=CL_0000057.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Pro (c.536A>C); ClinVar=VCV000376611; Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2998 (KMST-6)
Sex of cell Female
Age at sampling 9FW
Category Transformed cell line
Publications

PubMed=1537630; DOI=10.1002/ijc.2910500426
Koichiro Mihara, Li-Yan Bai, Yoshio Kano, Masahiro Miyazaki, Masayoshi Namba;
Malignant transformation of human fibroblasts previously immortalized with 60Co gamma rays.
Int. J. Cancer 50:639-643(1992)

PubMed=8601579; DOI=10.1007/BF01209654
Israt Jahan, Mikio Iijima, Tadashi Kondo, Masayoshi Namba;
Effects of okadaic acid on cell growth, anchorage-independent growth, and co-cultures of normal (KMS-6), immortalized (KMST-6), and neoplastically transformed (KMST-6T and KMST-6/RAS) human fibroblasts.
J. Cancer Res. Clin. Oncol. 122:249-253(1996)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

Cross-references
Cell line collections (Providers) JCRB; JCRB0434 - Discontinued
Anatomy/cell type resources BTO; BTO_0002040
Encyclopedic resources Wikidata; Q54900191
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20