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Cellosaurus KMST-6/T (CVCL_2999)

[Text version]
Cell line name KMST-6/T
Accession CVCL_2999
Resource Identification Initiative To cite this cell line use: KMST-6/T (RRID:CVCL_2999)
Comments Population: Japanese.
Characteristics: Tumorigenic. Established from 2nd-passage tumors obtained in nude mice by transplanting one of the primary tumors produced by subcutaneous inoculation of KMST-6 cells into nude mice.
Doubling time: 37 +- 4.6 hours (Note=In 10% FBS), 47 +- 2.9 hours (Note=In 1% FBS) (PubMed=1537630).
Transformant: NCIt; C129640; Cobalt-60 gamma radiation.
Derived from site: In situ; Whole fetus; UBERON=UBERON_0000323.
Cell type: Fibroblast; CL=CL_0000057.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.His179Pro (c.536A>C); ClinVar=VCV000376611; Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2998 (KMST-6)
Sex of cell Female
Age at sampling 9FW
Category Transformed cell line
Publications

PubMed=1537630; DOI=10.1002/ijc.2910500426
Mihara K., Bai L., Kano Y., Miyazaki M., Namba M.
Malignant transformation of human fibroblasts previously immortalized with 60Co gamma rays.
Int. J. Cancer 50:639-643(1992)

PubMed=8601579; DOI=10.1007/BF01209654
Jahan I., Iijima M., Kondo T., Namba M.
Effects of okadaic acid on cell growth, anchorage-independent growth, and co-cultures of normal (KMS-6), immortalized (KMST-6), and neoplastically transformed (KMST-6T and KMST-6/RAS) human fibroblasts.
J. Cancer Res. Clin. Oncol. 122:249-253(1996)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

Cross-references
Cell line collections (Providers) JCRB; JCRB0434 - Discontinued
Anatomy/cell type resources BTO; BTO:0002040
Encyclopedic resources Wikidata; Q54900191
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number19