ID   KMST-6/T
AC   CVCL_2999
DR   BTO; BTO_0002040
DR   JCRB; JCRB0434
DR   Wikidata; Q54900191
RX   PubMed=1537630;
RX   PubMed=8601579;
RX   PubMed=9290701;
CC   Population: Japanese.
CC   Characteristics: Tumorigenic. Established from 2nd-passage tumors obtained in nude mice by transplanting one of the primary tumors produced by subcutaneous inoculation of KMST-6 cells into nude mice.
CC   Doubling time: 37 +- 4.6 hours (Note=In 10% FBS), 47 +- 2.9 hours (Note=In 1% FBS) (PubMed=1537630).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Pro (c.536A>C); ClinVar=VCV000376611; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCIt; C129640; Cobalt-60 gamma radiation.
CC   Discontinued: JCRB; JCRB0434; true.
CC   Derived from site: In situ; Whole fetus; UBERON=UBERON_0000323.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2998 ! KMST-6
SX   Female
AG   9FW
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 20
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RX   PubMed=8601579; DOI=10.1007/BF01209654;
RA   Jahan, Israt
RA   Iijima, Mikio
RA   Kondo, Tadashi
RA   Namba, Masayoshi
RT   "Effects of okadaic acid on cell growth, anchorage-independent growth,
RT   and co-cultures of normal (KMS-6), immortalized (KMST-6), and
RT   neoplastically transformed (KMST-6T and KMST-6/RAS) human
RT   fibroblasts.";
RL   J. Cancer Res. Clin. Oncol. 122:249-253(1996).
//
RX   PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D;
RA   Jia, Li-Qun
RA   Osada, Motonobu
RA   Ishioka, Chikashi
RA   Gamo, Makio
RA   Ikawa, Shuntaro
RA   Suzuki, Takao
RA   Shimodaira, Hideki
RA   Niitani, Tomohito
RA   Kudo, Toshio
RA   Akiyama, Mitoshi
RA   Kimura, Narimiti
RA   Matsuo, Mitsuyoshi
RA   Mizusawa, Hiroshi
RA   Tanaka, Noriho
RA   Koyama, Hideki
RA   Namba, Masayoshi
RA   Kanamaru, Ryunosuke
RA   Kuroki, Toshio
RT   "Screening the p53 status of human cell lines using a yeast functional
RT   assay.";
RL   Mol. Carcinog. 19:243-253(1997).
//
RX   PubMed=1537630; DOI=10.1002/ijc.2910500426;
RA   Mihara, Koichiro
RA   Bai, Li-Yan
RA   Kano, Yoshio
RA   Miyazaki, Masahiro
RA   Namba, Masayoshi
RT   "Malignant transformation of human fibroblasts previously immortalized
RT   with 60Co gamma rays.";
RL   Int. J. Cancer 50:639-643(1992).
//