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Cellosaurus KMST-6/p53 (CVCL_WH81)

[Text version]
Cell line name KMST-6/p53
Accession CVCL_WH81
Resource Identification Initiative To cite this cell line use: KMST-6/p53 (RRID:CVCL_WH81)
Comments Population: Japanese.
Transfected with: HGNC; 11998; TP53 (with p.Arg273His).
Transformant: NCIt; C129640; Cobalt-60 gamma radiation.
Derived from site: In situ; Whole fetus; UBERON=UBERON_0000323.
Cell type: Fibroblast; CL=CL_0000057.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.His179Pro (c.536A>C); ClinVar=VCV000376611; Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2998 (KMST-6)
Sex of cell Female
Age at sampling 9FW
Category Transformed cell line
Publications

DOI=10.11418/jtca1981.12.4_313
Namba M., Bai L., Kano Y., Sugihara S., Miyazaki M.
Multistep malignant transformation of human cells: immortalization of human fibroblasts by treatment with 60Co gamma rays and 4-nitroquinoline 1-oxide, and their malignant transformation with the ras oncogene.
Tissue Cult. Res. Commun. 12:313-318(1993)

PubMed=8148305
Namba M., Iijima M., Kondo T., Jahan I., Mihara K.
Immortalization of normal human cells is a multistep process and a rate limiting step of neoplastic transformation of the cells.
Hum. Cell 6:253-259(1993)

Cross-references
Encyclopedic resources Wikidata; Q94428564
Entry history
Entry creation24-May-2019
Last entry update29-Jun-2023
Version number10