| Publications | PubMed=3857372; DOI=10.1093/jnci/74.4.759
Robert H. Whitehead, Finlay A. Macrae, D. James B. St John, Jeng Ma;
A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer.
J. Natl. Cancer Inst. 74:759-765(1985) PubMed=1427983; DOI=10.1038/icb.1992.30
Robert H. Whitehead, Hui-Hua Zhang, Ian P. Hayward;
Retention of tissue-specific phenotype in a panel of colon carcinoma cell lines: relationship to clinical correlates.
Immunol. Cell Biol. 70:227-236(1992) PubMed=9328464; DOI=10.1093/hmg/6.12.2011
Andrzej Kilian, David D.L. Bowtell, Helen E. Abud, Gary R. Hime, Deon J. Venter, Paul K. Keese, Emma L. Duncan, Roger Robert Reddel, Richard Anthony Jefferson;
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.
Hum. Mol. Genet. 6:2011-2019(1997) PubMed=9515795
Andrew B. Sparks, Patrice J. Morin, Bert Vogelstein, Kenneth Wayne Kinzler;
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.
Cancer Res. 58:1130-1134(1998) PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001) PubMed=12615714
Paula M. Hempen, Lin Zhang, Ravi K. Bansal, Christine A. Iacobuzio-Donahue, Kathleen M. Murphy, Anirban Maitra, Bert Vogelstein, Robert H. Whitehead, Sanford David Markowitz, James K.V. Willson, Charles J. Yeo ...Show all 13 authors... , Ralph H. Hruban, Scott E. Kern; Show fewer authors
Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.
Cancer Res. 63:994-999(2003) PubMed=19378335; DOI=10.1002/ijc.24289
Hui-Hua Zhang, Francesca E. Walker, Sara Kiflemariam, Robert H. Whitehead, David Williams, Wayne A. Phillips, Thomas Mikeska, Alexander Dobrovic, Antony Wilks Burgess;
Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.
Int. J. Cancer 125:297-307(2009) PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192; PMCID=PMC2943514
Manickam Janakiraman, Efsevia Vakiani, Zhao-Shi Zeng, Christine A. Pratilas, Barry Stephen Taylor, Dhananjay Chitale, Ensar Halilovic, Manda Wilson, Kety Huberman, Julio Cezar Marques Ricarte Filho, Yogindra Persaud ...Show all 21 authors... , Douglas A. Levine, James Alexander Fagin, Suresh C. Jhanwar, John M. Mariadason, Alex Lash, Marc Ladanyi, Leonard B. Saltz, Adriana Heguy, Philip B. Paty, David B. Solit; Show fewer authors
Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Cancer Res. 70:5901-5911(2010) PubMed=22722830; DOI=10.1038/nature11156; PMCID=PMC3927413
Sandra Misale, Rona D. Yaeger, Sebastijan Hobor, Elisa Scala, Manickam Janakiraman, David Liska, Emanuele Valtorta, Roberta Schiavo, Michela Buscarino, Giulia Siravegna, Katia Bruna Bencardino ...Show all 26 authors... , Andrea Cercek, Chin-Tung Chen, Silvio Veronese, Carlo Zanon, Andrea Sartore-Bianchi, Marcello Gambacorta, Margherita Gallicchio, Efsevia Vakiani, Valentina Boscaro, Enzo Medico, Martin R. Weiser, Salvatore Siena, Federica Di Nicolantonio, David B. Solit, Alberto Bardelli; Show fewer authors
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
Nature 486:532-536(2012) PubMed=23458625; DOI=10.1021/pr3010869
Susan Fanayan, Joshua T. Smith, Ling Y. Lee, Fang-Fei Yan, Michael P. Snyder, William S. Hancock, Edouard Nice;
Proteogenomic analysis of human colon carcinoma cell lines LIM1215, LIM1899, and LIM2405.
J. Proteome Res. 12:1732-1742(2013) PubMed=24295106; DOI=10.1021/pr400861m
Manveen K. Sethi, Morten Thaysen-Andersen, Joshua T. Smith, Mark Scott Baker, Nicolle H. Packer, William S. Hancock, Susan Fanayan;
Comparative N-glycan profiling of colorectal cancer cell lines reveals unique bisecting GlcNAc and alpha-2,3-linked sialic acid determinants are associated with membrane proteins of the more metastatic/aggressive cell lines.
J. Proteome Res. 13:277-288(2014) PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013
Dmitri Mouradov, Clare Sloggett, Robert N. Jorissen, Christopher G. Love, Shan Li, Antony Wilks Burgess, Diego Arango, Robert L. Strausberg, Daniel Buchanan, Samuel Wormald, Liam O'Connor ...Show all 17 authors... , Jennifer L. Wilding, David C. Bicknell, Ian Philip Mark Tomlinson, Walter Fred Bodmer, John M. Mariadason, Oliver M. Sieber; Show fewer authors
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
Cancer Res. 74:3238-3247(2014) PubMed=25623215; DOI=10.1158/1078-0432.CCR-14-2821
Sabrina Arena, Beatriz Bellosillo, Giulia Siravegna, Alejandro Martinez, Israel Canadas, Luca Lazzari, Noelia Ferruz, Mariangela Russo, Sandra Misale, Iria Gonzalez, Mar Iglesias ...Show all 25 authors... , Elena Gavilan, Giorgio Corti, Sebastijan Hobor, Giovanni Crisafulli, Marta Salido, Juan Sanchez, Alba Dalmases, Joaquim Bellmunt, Gianni De Fabritiis, Ana Rovira, Federica Di Nicolantonio, Joan Albanell, Alberto Bardelli, Clara Montagut; Show fewer authors
Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer.
Clin. Cancer Res. 21:2157-2166(2015) PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015) PubMed=25944804; DOI=10.1158/1078-0432.CCR-14-2457
Sarah Bazzocco, Higinio Dopeso, Fernando Carton-Garcia, Irati Macaya, Elena Andretta, Fiona Chionh, Paulo Rodrigues, Miriam Garrido, Hafid Alazzouzi, Rocio Nieto, Alex Sanchez ...Show all 15 authors... , Simo Schwartz Jr., Josipa Bilic, John M. Mariadason, Diego Arango; Show fewer authors
Highly expressed genes in rapidly proliferating tumor cells as new targets for colorectal cancer treatment.
Clin. Cancer Res. 21:3695-3704(2015) PubMed=28854368; DOI=10.1016/j.celrep.2017.08.010; PMCID=PMC5583477
Theodoros I. Roumeliotis, Steven P. Williams, Emanuel Goncalves, Clara Alsinet, Martin Del Castillo Velasco-Herrera, Nanne Aben, Fatemeh Zamanzad Ghavidel, Magali Michaut, Michael Schubert, Stacey Price, James C. Wright ...Show all 24 authors... , Lu Yu, Mi Yang, Rodrigo Dienstmann, Justin H. Guinney, Pedro Beltrao, Alvis Brazma, Mercedes Pardo, Oliver Stegle, David J. Adams, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Jyoti S. Choudhary; Show fewer authors
Genomic determinants of protein abundance variation in colorectal cancer cells.
Cell Rep. 20:2201-2214(2017) PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019) |
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