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Cellosaurus L-5178-Y (CVCL_2097)

[Text version]
Cell line name L-5178-Y
Synonyms L5178Y; LY
Accession CVCL_2097
Resource Identification Initiative To cite this cell line use: L-5178-Y (RRID:CVCL_2097)
Comments Doubling time: 14.1 +- 1.6 hours (PubMed=221956); 11.3 hours (PubMed=6173370); ~20 hours (DSMZ=ACC-320); 10 hours (Note=Lot 07032005) (JCRB=JCRB0709).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse thymic lymphoma (NCIt: C134997)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Children:
CVCL_4234 (L-5178-Y-R)CVCL_C8YC (L5178Y Adh)CVCL_UZ88 (L5178Y BLM-A2-R)
CVCL_L282 (L5178Y LX821)CVCL_L283 (L5178Y LX827)CVCL_7882 (L5178Y LX830)
CVCL_L284 (L5178Y M10)CVCL_J373 (L5178Y ts2)CVCL_J374 (L5178Y ts39)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line

Kessel D.H., Bosmann H.B.
On the characteristics of actinomycin D resistance in L5178Y cells.
Cancer Res. 30:2695-2701(1970)

PubMed=221956; DOI=10.2307/3575014
Sato K., Hieda N.
Isolation and characterization of a mutant mouse lymphoma cell sensitive to methyl methanesulfonate and X rays.
Radiat. Res. 78:167-171(1979)

PubMed=6173370; DOI=10.7164/antibiotics.34.1210
Suzuki H., Nishimura T., Tanaka N.
Drug sensitivity and some characteristics of a bleomycin-resistant subline of mouse lymphoblastoma L5178Y cells.
J. Antibiot. 34:1210-1212(1981)

PubMed=6413855; DOI=10.1016/0165-7992(83)90215-4
Sato K., Hieda-Shiomi N., Hama-Inaba H.
X-ray-sensitive mutant mouse cells with various sensitivities to chemical mutagens.
Mutat. Res. 121:281-285(1983)

PubMed=6724617; DOI=10.1007/BF02619582
Ankel E.G., Zirneski J., Ring B.J., Holcenberg J.S.
Effect of asparaginase on cell membranes of sensitive and resistant mouse lymphoma cells.
In Vitro 20:376-384(1984)

PubMed=7565900; DOI=10.1016/0165-7992(95)00027-5
Zhang L.-S., Honma M., Hayashi M., Suzuki T., Matsuoka A., Sofuni T.
A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test.
Mutat. Res. 347:105-115(1995)

PubMed=15033590; DOI=10.1289/ehp.6709
Newton R.K., Aardema M.J., Aubrecht J.
The utility of DNA microarrays for characterizing genotoxicity.
Environ. Health Perspect. 112:420-422(2004)

Cell line collections (Providers) DSMZ; ACC-320
ECACC; 87111908
RCB; RCB0135
Cell line databases/resources CLO; CLO_0007195
CLO; CLO_0050168
CLDB; cl3133
DSMZCellDive; ACC-320
Lonza; 1262
Anatomy/cell type resources BTO; BTO:0000795
Chemistry resources ChEMBL-Cells; CHEMBL3307690
ChEMBL-Targets; CHEMBL614720
PubChem_Cell_line; CVCL_2097
Encyclopedic resources Wikidata; Q54900871
Gene expression databases ArrayExpress; E-TOXM-1
ArrayExpress; E-TOXM-2
ArrayExpress; E-TOXM-3
ArrayExpress; E-TOXM-4
ArrayExpress; E-TOXM-5
ArrayExpress; E-TOXM-6
ArrayExpress; E-TOXM-7
ArrayExpress; E-TOXM-8
ArrayExpress; E-TOXM-9
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18