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Cellosaurus L-5178-Y-R (CVCL_4234)

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Cell line name L-5178-Y-R
Synonyms L5178Y-R; L5178YR; L5178-R; LY-R; LYR
Accession CVCL_4234
Resource Identification Initiative To cite this cell line use: L-5178-Y-R (RRID:CVCL_4234)
Comments Characteristics: Resistant to X-rays, but sensitive to ultraviolet radiation.
Doubling time: ~12-15 hours (PubMed=6883332).
Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse thymic lymphoma (NCIt: C134997)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_2097 (L-5178-Y)
Children:
CVCL_4235 (L-5178-Y-S)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line
Publications

PubMed=6883332
Janusz Zygmunt Beer, Ewa Budzicka, Elzbieta Niepokojczycka, Olgierd Rosiek, Irena Szumiel, Mafgorzata Walicka;
Loss of tumorigenicity with simultaneous changes in radiosensitivity and photosensitivity during in vitro growth of L5178Y murine lymphoma cells.
Cancer Res. 43:4736-4742(1983)

PubMed=3876312; DOI=10.1080/09553008514551671
Janusz Zygmunt Beer, Jaroslav Mencl, Min-Fen Horng, Earle C. Gregg, Helen Harrington Evans;
Effects of low dose rate (0.003-0.025 Gy/h) chronic X-irradiation on radioresistant and radiosensitive L5178Y mouse lymphoma cells.
Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 48:609-619(1985)

PubMed=3012566; DOI=10.1073/pnas.83.12.4379; PMCID=PMC323736
Helen Harrington Evans, Jaroslav Mencl, Min-Fen Horng, Marlene Ricanati, Carlos Sanchez, John C. Hozier;
Locus specificity in the mutability of L5178Y mouse lymphoma cells: the role of multilocus lesions.
Proc. Natl. Acad. Sci. U.S.A. 83:4379-4383(1986)

Cross-references
Cell line collections (Providers) ATCC; CRL-1722
CLS; 400258
ECACC; 90062802
KCLB; 21722
Cell line databases/resources CLO; CLO_0007193
CLO; CLO_0007197
CLDB; cl3135
Encyclopedic resources Wikidata; Q54900872
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number14