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Cellosaurus S1 (CVCL_0H88)

[Text version]
Cell line name S1
Accession CVCL_0H88
Resource Identification Initiative To cite this cell line use: S1 (RRID:CVCL_0H88)
Comments Population: Caucasian.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations
  • Mutation; HGNC; 2514; CTNNB1; Simple; p.Ser45Phe (c.134C>T); ClinVar=VCV000017588; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1384 (LS174T)
CVCL_0H85 (S1-B1-20)CVCL_A9DE (S1-IR20)CVCL_0H86 (S1-M1-3.2)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line

Zhang X.P., Ritke M.K., Yalowich J.C., Slovak M.L., Ho J.P., Collins K.I., Annable T., Arceci R.J., Durr F.E., Greenberger L.M.
P-glycoprotein mediates profound resistance to bisantrene.
Oncol. Res. 6:291-301(1994)

Cell line databases/resources cancercelllines; CVCL_0H88
Chemistry resources ChEMBL-Cells; CHEMBL4630771
ChEMBL-Targets; CHEMBL4630779
PubChem_Cell_line; CVCL_0H88
Encyclopedic resources Wikidata; Q54951787
Entry history
Entry creation10-Apr-2015
Last entry update05-Oct-2023
Version number14