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Cellosaurus S1 (CVCL_0H88)

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Cell line name S1
Accession CVCL_0H88
Resource Identification Initiative To cite this cell line use: S1 (RRID:CVCL_0H88)
Comments Population: Caucasian.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45Phe (c.134C>T); ClinVar=VCV000017588; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1384 (LS174T)
Children:
CVCL_0H85 (S1-B1-20)CVCL_A9DE (S1-IR20)CVCL_0H86 (S1-M1-3.2)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=7865904
Xiao-Ping Zhang, Mary K. Ritke, Jack Charles Yalowich, Marilyn L. Slovak, Jennifer Pelkey Ho, Karen I. Collins, Tami Annable, Robert John Arceci, Frederick E. Durr, Lee M. Greenberger;
P-glycoprotein mediates profound resistance to bisantrene.
Oncol. Res. 6:291-301(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0H88
Chemistry resources ChEMBL-Cells; CHEMBL4630771
ChEMBL-Targets; CHEMBL4630779
PubChem_Cell_line; CVCL_0H88
Encyclopedic resources Wikidata; Q54951787
Entry history
Entry creation10-Apr-2015
Last entry update19-Dec-2024
Version number15