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Cellosaurus IMR-32 (CVCL_0346)

[Text version]
Cell line name IMR-32
Synonyms IMR 32; IMR32; Institute for Medical Research-32; GM03320; GM3320C; GM03320D; AG03320; AG3320
Accession CVCL_0346
Resource Identification Initiative To cite this cell line use: IMR-32 (RRID:CVCL_0346)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Characteristics: Neuroblastic type (N-type).
Doubling time: 48 hours (PubMed=5459762); ~20 hours (ATCC=CCL-127); ~40-50 hours (DSMZ=ACC-165).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; Subcellular; Cell surface.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Misspelling: IMR-92; Note=Occasionally.
Misspelling: IRM-32; Note=Occasionally.
Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916.
HLA typing Source: PubMed=26589293
Class I
HLA-AA*24:02,24:02
HLA-BB*07:05,07:05
HLA-CC*05:01,12:03
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.56
East Asian, North1.01
East Asian, South0
South Asian3.99
European, North73.7
European, South20.72
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B0GV (I3.4.2)CVCL_S028 (IMR-32 SimpleCell O-GalNAc)CVCL_A9J0 (IMR-32/CMV-Luc)
CVCL_ER17 (IMR-32_pCMV-DPP3)CVCL_ER18 (IMR-32_pCMV-SQSTM1)CVCL_RS60 (IMR-32rBORTE10)
CVCL_ZX18 (IMR-32rCARBO1000)CVCL_RR66 (IMR-32rCARBO4000)CVCL_RS61 (IMR-32rCARBO5000)
CVCL_RR67 (IMR-32rCDDP1000)CVCL_RS27 (IMR-32rCDDP500)CVCL_RR68 (IMR-32rDOX20)
CVCL_RR69 (IMR-32rETO100)CVCL_RS53 (IMR-32rGEMCI20)CVCL_RR70 (IMR-32rGEMCI25)
CVCL_RS54 (IMR-32rMEL2000)CVCL_RR71 (IMR-32rMEL500)CVCL_RR72 (IMR-32rOXALI4000)
CVCL_RS55 (IMR-32rOXALI800)CVCL_RS56 (IMR-32rTOPO20)CVCL_RR73 (IMR-32rTOPO7.5)
CVCL_RS57 (IMR-32rTOPO8)CVCL_RR36 (IMR-32rVCR10)CVCL_RS58 (IMR-32rVINOR20)
CVCL_RR75 (IMR-32rVINOR5)CVCL_1306 (IMR-5)CVCL_A8UT (IMR/KAT100)
CVCL_A8SG (IMR32.CMV.neo)CVCL_A8SH (IMR32.ODC.CE)
Sex of cell Male
Age at sampling 1Y1M
Category Cancer cell line
STR profile Source(s): ATCC=CCL-127; CCRID; CLS=300148; COG; DSMZ=ACC-165; IZSLER=BS TCL 29; JCRB=IFO50283; JCRB=JCRB9050; KCLB=10127; PubMed=25877200; PubMed=31581737; PubMed=33460449; RCB=RCB1895; TKG=TKG 0207

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133823,24
D3S135816
D5S81811,12
D7S8209,10
D8S117913
D13S3179
D16S5398 (ATCC=CCL-127; CCRID; COG; DSMZ=ACC-165; IZSLER=BS TCL 29; JCRB=IFO50283; JCRB=JCRB9050; PubMed=25877200; PubMed=31581737; PubMed=33460449; RCB=RCB1895; TKG=TKG 0207)
8,10 (CLS=300148)
D18S5112,15
D19S43314,15
D21S1130,31
FGA21,24
Penta D11,12
Penta E7,15
TH017,9.3 (ATCC=CCL-127; CCRID; CLS=300148; COG; DSMZ=ACC-165; IZSLER=BS TCL 29; JCRB=IFO50283; KCLB=10127; PubMed=25877200; PubMed=31581737; PubMed=33460449; RCB=RCB1895; TKG=TKG 0207)
7,10 (JCRB=JCRB9050)
TPOX11
vWA15

Run an STR similarity search on this cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/i/cell-lines-detail-508.html
Publications

PubMed=5459762
Joseph J. Tumilowicz, Warren W. Nichols, Jolanta J. Cholon, Arthur E. Greene;
Definition of a continuous human cell line derived from neuroblastoma.
Cancer Res. 30:2110-2118(1970)

DOI=10.1007/978-1-4757-1647-4_13
June Lee Biedler;
Chromosome abnormalities in human tumor cells in culture.
(In book chapter) Human tumor cells in vitro; Fogh, Jorgen (eds.); pp.359-394; Springer; New York; USA (1975)

PubMed=62055; DOI=10.1093/jnci/57.3.683
June Lee Biedler, Barbara A. Spengler;
A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture.
J. Natl. Cancer Inst. 57:683-695(1976)

PubMed=71759; DOI=10.1126/science.71759
Gloria Brady Balaban-Malenbaum, Fred Gilbert;
Double minute chromosomes and the homogeneously staining regions in chromosomes of a human neuroblastoma cell line.
Science 198:739-741(1977)

PubMed=327080; DOI=10.1093/jnci/59.1.221
Jorgen Fogh, Jens M. Fogh, Thomas Orfeo;
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Jorgen Fogh, William C. Wright, James D. Loveless;
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=922665; DOI=10.1002/1097-0142(197711)40:5<2256::AID-CNCR2820400536>3.0.CO;2-1
Garrett M. Brodeur, Gurbax Singh Sekhon, Milton N. Goldstein;
Chromosomal aberrations in human neuroblastomas.
Cancer 40:2256-2263(1977)

CLPUB00387
Lewis Lemon Coriell, Arthur E. Greene, Richard A. Mulivor;
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 7th edition. October 1980.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 80-2011; pp.1-254; National Institutes of Health; Bethesda; USA (1980)

PubMed=6935474; DOI=10.1093/jnci/66.2.239
William C. Wright, Walter P. Daniels, Jorgen Fogh;
Distinction of seventy-one cultured human tumor cell lines by polymorphic enzyme analysis.
J. Natl. Cancer Inst. 66:239-247(1981)

PubMed=7253718; DOI=10.1016/0047-6374(81)90027-0
Nirmal K. Das, Donald G. Murphy;
The National Institute on Aging repository cell cultures.
Mech. Ageing Dev. 16:1-17(1981)

PubMed=7459858
Monique Rousset, Alain Zweibaum, Jorgen Fogh;
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Cancer Res. 41:1165-1170(1981)

PubMed=7037175
Charles Patrick Reynolds, Debra A. Reynolds, Eugene Philip Frenkel, R. Graham Smith;
Selective toxicity of 6-hydroxydopamine and ascorbate for human neuroblastoma in vitro: a model for clearing marrow prior to autologous transplant.
Cancer Res. 42:1331-1336(1982)

PubMed=7139592; DOI=10.1016/0165-4608(82)90105-4
Fred Gilbert, Gloria Brady Balaban-Malenbaum, Paul Sidney Moorhead, Diana W. Bianchi, Harvey R. Schlesinger;
Abnormalities of chromosome 1p in human neuroblastoma tumors and cell lines.
Cancer Genet. Cytogenet. 7:33-42(1982)

DOI=10.1016/B978-0-12-008304-6.50015-4
June Lee Biedler, Marian B. Meyers, Barbara A. Spengler;
Homogeneously staining regions and double minute chromosomes, prevalent cytogenetic abnormalities of human neuroblastoma cells.
(In book chapter) Advances in cellular neurobiology, Vol. 4; Fedoroff, Sergey & Hertz, Leif (eds.); pp.267-307; Academic Press; New York; USA (1983)

PubMed=6401685; DOI=10.1007/BF02617989
David Michael Halton, Ward Davis Peterson Jr., Bharati Hukku;
Cell culture quality control by rapid isoenzymatic characterization.
In Vitro 19:16-24(1983)

PubMed=6888561; DOI=10.1038/305245a0
Manfred Schwab, Kari Alitalo, Karl-Heinz Klempnauer, Harold Eliot Varmus, John Michael Bishop, Fred Gilbert, Garrett M. Brodeur, Milton N. Goldstein, Jeffrey M. Trent;
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.
Nature 305:245-248(1983)

PubMed=3518877; DOI=10.3109/07357908609038260
Jorgen Fogh;
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=3698005
Marvin D. Bregman, Carole Funk, Masanori Fukushima;
Inhibition of human melanoma growth by prostaglandin A, D, and J analogues.
Cancer Res. 46:2740-2744(1986)

PubMed=2535691
Valentina C. Ciccarone, Barbara A. Spengler, Marian B. Meyers, June Lee Biedler, Robert A. Ross;
Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages.
Cancer Res. 49:219-225(1989)

PubMed=8221663
Hiroaki Komuro, Yasuhide Hayashi, Machiko Kawamura, Kenshi Hayashi, Yasuhiko Kaneko, Shigehiko Kamoshita, Ryoji Hanada, Keiko Yamamoto, Teruaki Hongo, Masao Yamada, Yoshiaki Tsuchida;
Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas.
Cancer Res. 53:5284-5288(1993)

PubMed=8490657; DOI=10.1038/ng0193-62
Inge The, Anita E. Murthy, Gregory E. Hannigan, Lee B. Jacoby, Anil G. Menon, James Francis Gusella, Andre Bernards;
Neurofibromatosis type 1 gene mutations in neuroblastoma.
Nat. Genet. 3:62-66(1993)

DOI=10.1016/B978-0-12-333530-2.50006-X
Mark A. Israel, Carol Jeanne Thiele;
Tumor cell lines of the peripheral nervous system.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.43-78; Academic Press; New York; USA (1994)

PubMed=7838528
Ngan Ching Cheng, Nadine Van Roy, Alvin Chan, Mabel Beitsma, Andries Westerveld, Frank Speleman, Rogier Versteeg;
Deletion mapping in neuroblastoma cell lines suggests two distinct tumor suppressor genes in the 1p35-36 region, only one of which is associated with N-myc amplification.
Oncogene 10:291-297(1995)

PubMed=8665486; DOI=10.1016/0304-3835(96)04250-4
Mitchell B. Diccianni, Lan S. Chau, Ayse Batova, Thai Q. Vu, Alice Lin-Tsing Yu;
The p16 and p18 tumor suppressor genes in neuroblastoma: implications for drug resistance.
Cancer Lett. 104:183-192(1996)

PubMed=9201287
Jindrich Cinatl Jr., Pablo Hernaiz Driever, Jaroslaw Cinatl, Dieter G. Ruckert, Hermann O.C. Gumbel, Holger F. Rabenau, Bernhard Kornhuber, Hans-Wilhelm Doerr;
Increased efficacy of aphidicolin killing of human neuroblastoma cells in vitro by encapsulation in liposomes.
Neoplasma 44:91-95(1997)

PubMed=9283597; DOI=10.1016/S0165-4608(96)00362-7
Nadine Van Roy, Anna Jauch, Mireille Van Gele, Genevieve Laureys, Rogier Versteeg, Anne De Paepe, Thomas Cremer, Frank Speleman;
Comparative genomic hybridization analysis of human neuroblastomas: detection of distal 1p deletions and further molecular genetic characterization of neuroblastoma cell lines.
Cancer Genet. Cytogenet. 97:135-142(1997)

PubMed=9516836; DOI=10.1016/S0959-8049(97)00319-5
Nadine Van Roy, Genevieve Laureys, Mireille Van Gele, Ghislain Opdenakker, R. Miura, Pauline van der Drift, Alvin Chan, Rogier Versteeg, Frank Speleman;
Analysis of 1;17 translocation breakpoints in neuroblastoma: implications for mapping of neuroblastoma genes.
Eur. J. Cancer 33:1974-1978(1997)

DOI=10.1007/0-306-46872-7_2
Carol Jeanne Thiele;
Neuroblastoma.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999)

PubMed=11550280; DOI=10.1002/gcc.1174
Nadine Van Roy, Heidi Van Limbergen, Jo Vandesompele, Mireille Van Gele, Bruce Poppe, Helen R. Salwen, Genevieve Laureys, Nunes Manoel, Anne De Paepe, Frank Speleman;
Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines.
Genes Chromosomes Cancer 32:126-135(2001)

PubMed=11668190; DOI=10.1177/002215540104901105
Hilmar Quentmeier, Mary Osborn, Julia Reinhardt, Margarete Zaborski, Hans Gunther Drexler;
Immunocytochemical analysis of cell lines derived from solid tumors.
J. Histochem. Cytochem. 49:1369-1378(2001)

PubMed=12210830; DOI=10.1002/jnr.10330
Shinobu Yoshida, Tsutomu Narita, Takashi Taga, Shigeru Ohta, Yoshihiro Takeuchi;
Malignant rhabdoid tumor shows incomplete neural characteristics as revealed by expression of SNARE complex.
J. Neurosci. Res. 69:642-652(2002)

PubMed=12702577
Fumiko Saito-Ohara, Issei Imoto, Jun Inoue, Hajime Hosoi, Akira Nakagawara, Tohru Sugimoto, Johji Inazawa;
PPM1D is a potential target for 17q gain in neuroblastoma.
Cancer Res. 63:1876-1883(2003)

PubMed=15390183; DOI=10.1002/gcc.20096
Sigrun Gebauer, Alice Lin-Tsing Yu, Motoko Omura-Minamisawa, Ayse Batova, Mitchell B. Diccianni;
Expression profiles and clinical relationships of ID2, CDKN1B, and CDKN2A in primary neuroblastoma.
Genes Chromosomes Cancer 41:297-308(2004)

PubMed=15892104; DOI=10.1002/gcc.20198
Yael P. Mosse, Joel Greshock, Adam A. Margolin, Tara Naylor, Kristina A. Cole, Deepa Khazi, George Hii, Cynthia Winter, Syed Shahzad, Muhammad Usman Asziz, Jaclyn A. Biegel ...Show all 13 authors... , Barbara L. Weber, John Matthew Maris; Show fewer authors
High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
Genes Chromosomes Cancer 43:390-403(2005)

PubMed=16524757; DOI=10.1016/j.biocel.2006.01.007
Dennis G. Fry, Brian D. Dayton, Sevan J. Brodjian, Christopher Ogiela, Hanna Sidorowicz, Leigh J. Frost, Teresa McNally, Regina M. Reilly, Christine A. Collins;
Characterization of a neuronal cell line expressing native human melanin-concentrating hormone receptor 1 (MCHR1).
Int. J. Biochem. Cell Biol. 38:1290-1299(2006)

PubMed=16822308; DOI=10.1186/1471-2407-6-177; PMCID=PMC1533846
Vincent Dam, Brian T. Morgan, Pavel Mazanek, Michael D. Hogarty;
Mutations in PIK3CA are infrequent in neuroblastoma.
BMC Cancer 6:177.1-177.10(2006)

PubMed=17974978; DOI=10.1158/0008-5472.CAN-06-4345
Cheng-Yuan Xue, Michelle Haber, Claudia Flemming, Glenn Mark Marshall, Richard B. Lock, Karen L. MacKenzie, Katerina V. Gurova, Murray D. Norris, Andrei V. Gudkov;
p53 determines multidrug sensitivity of childhood neuroblastoma.
Cancer Res. 67:10351-10360(2007)

PubMed=20655465; DOI=10.1016/j.cell.2010.06.004; PMCID=PMC2913027
Michael Holzel, Si-Dong Huang, Jan Koster, Ingrid Ora, Arjan Lakeman, Huib Nicolaas Caron, Wouter Nijkamp, Jing Xie, Tom Callens, Shahab Asgharzadeh, Robert C. Seeger ...Show all 14 authors... , Ludwine M. Messiaen, Rogier Versteeg, Rene Bernards; Show fewer authors
NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome.
Cell 142:218-229(2010)

PubMed=22213050; DOI=10.1002/ijc.27415; PMCID=PMC3757132
Joanna E. Gawecka, Dirk Geerts, Jan Koster, Maisel J. Caliva, Florian J. Sulzmaier, John Opoku-Ansah, Randal K. Wada, Andre S. Bachmann, Joe W. Ramos;
PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma.
Int. J. Cancer 131:1556-1568(2012)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=24466371; DOI=10.1593/tlo.13544; PMCID=PMC3890703
Nadine Loschmann, Martin Michaelis, Florian Rothweiler, Richard Zehner, Jaroslaw Cinatl, Yvonne Voges, Mohsen Sharifi, Kristoffer Riecken, Jochen Meyer, Andreas von Deimling, Iduna Fichtner ...Show all 14 authors... , Taravat Ghafourian, Frank Westermann, Jindrich Cinatl Jr.; Show fewer authors
Testing of SNS-032 in a panel of human neuroblastoma cell lines with acquired resistance to a broad range of drugs.
Transl. Oncol. 6:685-696(2013)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347
Damaris Bausch-Fluck, Andreas Hofmann, Thomas Bock, Andreas P. Frei, Ferdinando Cerciello, Andrea Jacobs, Hansjoerg Moest, Ulrich Omasits, Rebekah L. Gundry, Charles Yoon, Ralph Schiess ...Show all 20 authors... , Alexander Schmidt, Paulina Mirkowska, Anetta Svitorka Hartlova, Jennifer Eileen Van Eyk, Jean-Pierre Bourquin, Rudolf Aebersold, Kenneth R. Boheler, Peter W. Zandstra, Bernd Wollscheid; Show fewer authors
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:e0121314.1-e0121314.22(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=28350380; DOI=10.1038/sdata.2017.33; PMCID=PMC5369315
Jo Lynne Harenza, Maura A. Diamond, Rebecca N. Adams, Michael M. Song, Heather L. Davidson, Lori S. Hart, Maiah H. Dent, Paolo Fortina, Charles Patrick Reynolds, John Matthew Maris;
Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.
Sci. Data 4:170033.1-170033.8(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31581737; DOI=10.3390/cells8101194; PMCID=PMC6830094
Jane F. Povey, Emily Saintas, Adewale Victor Aderemi, Florian Rothweiler, Richard Zehner, Wilhelm Gerhard Dirks, Jindrich Cinatl Jr., Andrew J. Racher, Mark N. Wass, Christopher Mark Smales, Martin Michaelis;
Intact-cell MALDI-ToF mass spectrometry for the authentication of drug-adapted cancer cell lines.
Cells 8:1194.1-1194.12(2019)

PubMed=33460449; DOI=10.1002/ijc.33474
Wilhelm Gerhard Dirks, Amanda Capes-Davis, Sonja Eberth, Silke Fahnrich, Jorg Wilting, Stefan Nagel, Laura Steenpass, Jennifer Becker;
Cross-contamination meets misclassification: awakening of CHP-100 from sleeping beauty sleep -- a reviewed model for Ewing's sarcoma.
Int. J. Cancer 148:2608-2613(2021)

Cross-references
Cell line collections (Providers) ABM; T8975
ATCC; CCL-127
BCRC; 60014
BCRJ; 0377
CCTCC; GDC0107
CLS; 300148
Coriell; AG03320 - Discontinued
Coriell; GM03320
DSMZ; ACC-165
ECACC; 86041809
ICLC; HTL96021
IZSLER; BS TCL 29
JCRB; IFO50283
JCRB; JCRB9050
KCB; KCB 2011100YJ
KCLB; 10127
RCB; RCB1895 - Discontinued
TKG; TKG 0207 - Discontinued
Cell line databases/resources CLO; CLO_0006948
CLO; CLO_0016777
MCCL; MCC:0000242
CLDB; cl2878
CLDB; cl2879
CLDB; cl2880
CLDB; cl2881
CLDB; cl2882
CLDB; cl2883
CLDB; cl2885
CLDB; cl2886
CLDB; cl2887
CLDB; cl2888
cancercelllines; CVCL_0346
CCRID; 1101HUM-PUMC000282
CCRID; 3101HUMTCHu145
CCRID; 4201HUM-CCTCC00107
Cell_Model_Passport; SIDM00226
CGH-DB; 78-1
CGH-DB; 9095-4
DepMap; ACH-000310
DSMZCellDive; ACC-165
LINCS_LDP; LCL-1965
Lonza; 971
Anatomy/cell type resources BTO; BTO_0000934
Biological sample resources BioSample; SAMN00808348
BioSample; SAMN03472412
BioSample; SAMN03473082
BioSample; SAMN10988103
CRISP screens repositories BioGRID_ORCS_Cell_line; 637
Chemistry resources ChEMBL-Cells; CHEMBL3307656
ChEMBL-Targets; CHEMBL614585
PharmacoDB; IMR32_659_2019
PubChem_Cell_line; CVCL_0346
Encyclopedic resources Wikidata; Q54897618
Experimental variables resources EFO; EFO_0001195
Gene expression databases ArrayExpress; E-MTAB-2706
ArrayExpress; E-MTAB-2770
GEO; GSM453632
GEO; GSM563362
GEO; GSM692859
GEO; GSM887162
GEO; GSM888234
GEO; GSM1366406
GEO; GSM1669934
GEO; GSM2371237
GEO; GSM2394364
Polymorphism and mutation databases Cosmic; 688067
Cosmic; 759892
Cosmic; 801746
Cosmic; 920239
Cosmic; 922658
Cosmic; 947702
Cosmic; 1019944
Cosmic; 1037352
Cosmic; 1099149
Cosmic; 1109111
Cosmic; 1237544
Cosmic; 1518066
Cosmic; 1526626
Cosmic; 2058113
Cosmic; 2131590
Cosmic; 2301580
Cosmic; 2393630
Cosmic; 2485944
IARC_TP53; 23585
LiGeA; CCLE_016
Progenetix; CVCL_0346
Proteomic databases PRIDE; PXD000589
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number50