Cellosaurus cell line IMR/KAT100 (CVCL

Cross-references
Cell line name	IMR/KAT100
Accession	CVCL_A8UT
Resource Identification Initiative	To cite this cell line use: IMR/KAT100 (RRID:CVCL_A8UT)
Comments	Population: Caucasian. Selected for resistance to: ChEBI; CHEBI_2761; Dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate (Antimony potassium tartrate; KAT). Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys135Phe (c.404G>T); ClinVar=VCV000376559; Zygosity=Homozygous (PubMed=17974978).
Disease	Neuroblastoma (NCIt: C3270) Neuroblastoma (ORDO: Orphanet_635)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0346 (IMR-32)
Sex of cell	Male
Age at sampling	1Y1M
Category	Cancer cell line
Publications	PubMed=17974978; DOI=10.1158/0008-5472.CAN-06-4345 Cheng-Yuan Xue, Michelle Haber, Claudia Flemming, Glenn Mark Marshall, Richard B. Lock, Karen L. MacKenzie, Katerina V. Gurova, Murray D. Norris, Andrei V. Gudkov; p53 determines multidrug sensitivity of childhood neuroblastoma. Cancer Res. 67:10351-10360(2007)
Cell line databases/resources	cancercelllines; CVCL_A8UT
Encyclopedic resources	Wikidata; Q108820545
Polymorphism and mutation databases	IARC_TP53; 26505
Entry history
Entry creation	23-Sep-2021
Last entry update	19-Dec-2024
Version number	6