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Cellosaurus IMR32.ODC.CE (CVCL_A8SH)

[Text version]
Cell line name IMR32.ODC.CE
Synonyms IMR32pIRES.ODC.CE
Accession CVCL_A8SH
Resource Identification Initiative To cite this cell line use: IMR32.ODC.CE (RRID:CVCL_A8SH)
Comments Population: Caucasian.
Characteristics: Expresses the carboxylesterase (CE) gene under the control of an ornithine decarboxylase (ODC) promoter (PubMed=10933967).
Transfected with: UniProtKB; P12337; Rabbit liver carboxylesterase 1.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0346 (IMR-32)
Sex of cell Male
Age at sampling 1Y1M
Category Cancer cell line
Publications

PubMed=10933967; DOI=10.1006/mthe.2000.0064
Pawlik C.A., Iyengar R.V., Krull E.J., Mason S.E., Khanna R., Harris L.C., Potter P.M., Danks M.K., Guichard S.M.
Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11.
Mol. Ther. 1:457-463(2000)

Cross-references
Encyclopedic resources Wikidata; Q108820547
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number4