Cellosaurus HuT 78 (CVCL_0337)
Cell line name | HuT 78 | ||||||||||||||||||||||||||||||||||||
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Synonyms | Hut 78; HUT 78; HuT-78; HUT-78; HuT78; Hut78; HUT78; NCI-H78 | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_0337 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: HuT 78 (RRID:CVCL_0337) | ||||||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981). Population: Caucasian. Doubling time: 26 hours (PubMed=6244013); 26 hours (HIVReagentProgram); ~65 hours (ATCC=TIB-161). Omics: Deep exome analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Omics: Virome analysis using RNAseq. Anecdotal: For a number of years it was not known that H9 used by Gallo's lab to isolate HIV-1 (HTLV-III) was in fact a clone of Hut 78 from Minna's lab (PubMed=2567177). This created a controversy between the labs of Minna and Gallo (PubMed=2193399). Derived from sampling site: Peripheral blood. Cell type=T-cell. | ||||||||||||||||||||||||||||||||||||
Sequence variations |
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Genome ancestry | Source: PubMed=30894373
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Disease | Sezary syndrome (NCIt: C3366) Sezary syndrome (ORDO: Orphanet_3162) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Hierarchy | Children:
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Sex of cell | Male | ||||||||||||||||||||||||||||||||||||
Age at sampling | 53Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC; CCRID; CLS; PubMed=11416159; PubMed=25877200; RCB; TKG Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-70.html http://www.nibsc.org/Default.aspx?pageid=597&id=0002&theme=default | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=6244013; DOI=10.1182/blood.V55.3.409.409 PubMed=6975346; DOI=10.1084/jem.154.5.1403 PubMed=6954533; DOI=10.1073/pnas.79.7.2194 PubMed=6151082; DOI=10.1016/s0140-6736(84)91666-0 PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0 PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1 PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x PubMed=3495441; DOI=10.1002/eji.1830170503 PubMed=2144611; DOI=10.1128/mcb.10.10.5502-5509.1990 PubMed=2193399; DOI=10.1126/science.2193399 PubMed=8127147 PubMed=8806089; DOI=10.1002/jcb.240630502 PubMed=8806090; DOI=10.1002/jcb.240630503 PubMed=8806092; DOI=10.1002/jcb.240630505 PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x PubMed=10570904; DOI=10.1007/s100380050178 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=12068308; DOI=10.1038/nature00766 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=22460905; DOI=10.1038/nature11003 PubMed=25355872; DOI=10.1128/JVI.02570-14 PubMed=30285677; DOI=10.1186/s12885-018-4840-5 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections | ATCC; TIB-161
ATCC; CRM-TIB-161 BCRC; 60522 BCRJ; 0370 CCTCC; GDC0307 CLS; 300338 ECACC; 88041901 HIVReagentProgram; ARP-89 KCLB; 90078 NCBI_Iran; C185 RCB; RCB1934 TKG; TKG 0375 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0004304
CLO; CLO_0051010 MCCL; MCC:0000233 CLDB; cl1778 CLDB; cl1779 CCRID; 1101HUM-PUMC000190 CCRID; 3101HUMTCHu206 Cell_Model_Passport; SIDM00851 CGH-DB; 9026-4 DepMap; ACH-000509 IGRhCellID; HuT78 LINCS_LDP; LCL-2005 Lonza; 813 TOKU-E; 1977 | ||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0001945 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN01821566
BioSample; SAMN03471940 BioSample; SAMN03473203 BioSample; SAMN10987600 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307500
ChEMBL-Targets; CHEMBL613978 PharmacoDB; HuT78_647_2019 PubChem_Cell_line; CVCL_0337 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54896909 | ||||||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0002209 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-2770 GEO; GSM887154 GEO; GSM888226 GEO; GSM1374569 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 724829
Cosmic; 1551450 Cosmic; 2153070 Cosmic; 2402468 Cosmic; 2765583 IARC_TP53; 185 LiGeA; CCLE_696 Progenetix; CVCL_0337 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 21-Mar-2023 | ||||||||||||||||||||||||||||||||||||
Version number | 35 |