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Cellosaurus HUT 78/HIV-2D194 (CVCL_X682)

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Cell line name HUT 78/HIV-2D194
Synonyms HUT 78 HIV-2 D194-Infected
Accession CVCL_X682
Resource Identification Initiative To cite this cell line use: HUT 78/HIV-2D194 (RRID:CVCL_X682)
Comments Population: Caucasian.
Virology: Infected with HIV-2 isolate D194 (BEI_Resources=ARP-1119).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene deletion; HGNC; HGNC:7208; MPDZ; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
Disease Sezary syndrome (NCIt: C3366)
Sezary syndrome (ORDO: Orphanet_3162)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0337 (HuT 78)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=2467304; DOI=10.1073/pnas.86.7.2383; PMCID=PMC286917
Herbert Kuhnel, Hagen von Briesen, Ursula Dietrich, Michalina Adamski, Detlef Mix, Lothar Biesert, Renate Kreutz, Andreas Immelmann, Karsten Henco, Christoph Meichsner, Reinhard Andreesen ...Show all 13 authors... , Hans R. Gelderblom, Helga Rubsamen-Schaeff; Show fewer authors
Molecular cloning of two West African human immunodeficiency virus type 2 isolates that replicate well in macrophages: a Gambian isolate, from a patient with neurologic acquired immunodeficiency syndrome, and a highly divergent Ghanian isolate.
Proc. Natl. Acad. Sci. U.S.A. 86:2383-2387(1989)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-1119
Cell line databases/resources cancercelllines; CVCL_X682
Encyclopedic resources Wikidata; Q54896911
Entry history
Entry creation05-Sep-2014
Last entry update19-Dec-2024
Version number16