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Cellosaurus HUT 78/SIVmac251 (CVCL_X609)

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Cell line name HUT 78/SIVmac251
Synonyms HUT-78-SIVmac251
Accession CVCL_X609
Resource Identification Initiative To cite this cell line use: HUT 78/SIVmac251 (RRID:CVCL_X609)
Comments Population: Caucasian.
Virology: Infected with simian immunodeficiency virus isolate SIVmac251 (BEI_Resources=ARP-160).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene deletion; HGNC; HGNC:7208; MPDZ; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
Disease Sezary syndrome (NCIt: C3366)
Sezary syndrome (ORDO: Orphanet_3162)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0337 (HuT 78)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=3159089; DOI=10.1126/science.3159089
Muthiah Devakadadcham Daniel, Norman Lee Letvin, Norval W. King Jr., Mari Kannagi, Prabhat K. Sehgal, Ronald Duncan Hunt, Phyllis Jean Kanki, Myron Elmer Essex, Ronald Charles Desrosiers;
Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.
Science 228:1201-1204(1985)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-160
Cell line databases/resources cancercelllines; CVCL_X609
Encyclopedic resources Wikidata; Q54896915
Entry history
Entry creation05-Sep-2014
Last entry update19-Dec-2024
Version number16