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Cellosaurus HuT 78/HIV-1 FRE-3 clone E2D (CVCL_D3XW)

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Cell line name HuT 78/HIV-1 FRE-3 clone E2D
Accession CVCL_D3XW
Resource Identification Initiative To cite this cell line use: HuT 78/HIV-1 FRE-3 clone E2D (RRID:CVCL_D3XW)
Comments Population: Caucasian.
Virology: Infected with HIV-1 isolate FRE-3 (Frederick isolate #3). Does not produce any muture gag proteins (PubMed=2231688).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene deletion; HGNC; HGNC:7208; MPDZ; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
Disease Sezary syndrome (NCIt: C3366)
Sezary syndrome (ORDO: Orphanet_3162)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0337 (HuT 78)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=2231688; DOI=10.1111/j.1600-0684.1990.tb00441.x
Raoul E. Benveniste, Richard W. Hill, Lawrence J. Eron, Ulrike M. Csaikl, Walter B. Knott, Louis E. Henderson, Raymond C. Sowder, Kunio Nagashima, Matthew A. Gonda;
Characterization of clones of HIV-1 infected HuT 78 cells defective in gag gene processing and of SIV clones producing large amounts of envelope glycoprotein.
J. Med. Primatol. 19:351-366(1990)

Cross-references
Encyclopedic resources Wikidata; Q127381963
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3