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Cellosaurus PM1 (CVCL_9472)

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Cell line name PM1
Accession CVCL_9472
Resource Identification Initiative To cite this cell line use: PM1 (RRID:CVCL_9472)
Comments Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene deletion; HGNC; HGNC:7208; MPDZ; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
Disease Sezary syndrome (NCIt: C3366)
Sezary syndrome (ORDO: Orphanet_3162)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0337 (HuT 78)
Children:
CVCL_YX97 (PM1-Luc)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=7745720; DOI=10.1128/JVI.69.6.3712-3720.1995; PMCID=PMC189087
Paolo Lusso, Fiorenza Cocchi, Claudia Balotta, Phillip D. Markham, Audrey Louie, Patrizia Farci, Ranajit Pal, Robert Charles Gallo, Marvin S. Reitz Jr.;
Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1.
J. Virol. 69:3712-3720(1995)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-3038
Cell line databases/resources cancercelllines; CVCL_9472
Encyclopedic resources Wikidata; Q54947607
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number22