Cellosaurus C2C12 (CVCL_0188)
Cell line name | C2C12 | ||||||||||||||||||||||||||||||||
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Synonyms | C2c12; C2-C12; C12 | ||||||||||||||||||||||||||||||||
Accession | CVCL_0188 | ||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: C2C12 (RRID:CVCL_0188) | ||||||||||||||||||||||||||||||||
Comments | Part of: ENCODE project mouse cell lines. Characteristics: Capable, upon starvation, of differentiating into contractile myotubes that express muscle-specific proteins. Doubling time: 19.6 +- 0.4 hours (Note=At 22th passage), 18.4 +- 0.2 hours (Note=At 38th passage) (PubMed=22020321); ~20 hours (DSMZ=ACC-565). Omics: Genomics; ChIP-seq; H3K27me3. Omics: Genomics; ChIP-seq; H3K36me3. Omics: Genomics; ChIP-seq; H3K4me3. Omics: Genomics; ChIP-seq; H3K79me2. Omics: Genomics; ChIP-seq; H3K79me3. Omics: Metabolomics. Omics: Proteomics. Omics: Proteomics; PTM; Glycoproteome. Omics: Proteomics; Subcellular; Cell surface. Omics: Transcriptomics; Microarray. Omics: Variations; SNP array analysis. Misspelling: C1C12; Note=Occasionally. Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134. Cell type: Myoblast; CL=CL_0000056. | ||||||||||||||||||||||||||||||||
Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C3H. | ||||||||||||||||||||||||||||||||
Hierarchy | Parent: CVCL_6812 (C2 [Mouse myoblast]) Children:
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Sex of cell | Female | ||||||||||||||||||||||||||||||||
Age at sampling | 2M | ||||||||||||||||||||||||||||||||
Category | Spontaneously immortalized cell line | ||||||||||||||||||||||||||||||||
STR profile | Source(s): Ubigene=YC-A010 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||
Web pages | Info; -; -; https://web.archive.org/web/20130502024425/http://www.stanford.edu/group/blau/protocols/c2lineprotocol.html Info; ECACC; -; https://www.culturecollections.org.uk/products/cell-cultures/ecacc-cell-line-profiles/c2c12/ Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-123.html Info; Wikipedia; -; https://en.wikipedia.org/wiki/C2C12 Provider; BRICS; BRICS0089; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3902 | ||||||||||||||||||||||||||||||||
Publications | PubMed=563524; DOI=10.1038/270725a0 PubMed=8023908; DOI=10.1152/ajpcell.1994.266.6.C1795 PubMed=15596414 PubMed=19298647; DOI=10.1186/1471-2121-10-20; PMCID=PMC2663541 PubMed=19350625; DOI=10.1002/bit.22318 PubMed=19656770; DOI=10.1074/mcp.M900195-MCP200; PMCID=PMC2773721 PubMed=20635352; DOI=10.1002/bit.22865 PubMed=22020321; DOI=10.1016/j.yexcr.2011.10.004; PMCID=PMC3541016 PubMed=24735950; DOI=10.1016/j.scr.2014.03.004 PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738 PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347 | ||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||
Cell line collections (Providers) | Abcam; ab279976
AddexBio; P0028001/4665 ATCC; CRL-1772 BCRC; 60083 BCRJ; 0058 CCTCC; GDC0175 CLS; 400476 DSMZ; ACC-565 ECACC; 91031101 IZSLER; BS CL 148 KCB; KCB 2012115YJ NCBI_Iran; C521 RCB; RCB0987 Ubigene; YC-A010 | ||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0002071
CLO; CLO_0050871 MCCL; MCC:0000079 CLDB; cl563 CLDB; cl564 CLDB; cl5172 CCRID; 1101MOU-PUMC000099 CCRID; 3101MOUGNM26 CCRID; 3101MOUSCSP505 CCRID; 4201MOU-CCTCC00175 DSMZCellDive; ACC-565 FCS-free; 221-17-457-3-4-3 FCS-free; 221-17-505-3-4-12 FCS-free; 221-21-488-3-4-12 FCS-free; 221-5-486-3-3 FCS-free; 221-5-527-1-3-3 Lonza; 692 TOKU-E; 728 | ||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO_0000165 | ||||||||||||||||||||||||||||||||
Biological sample resources | ENCODE; ENCBS124ENC
ENCODE; ENCBS299ZOZ ENCODE; ENCBS981MXJ | ||||||||||||||||||||||||||||||||
CRISP screens repositories | BioGRID_ORCS_Cell_line; 1564 | ||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308003
ChEMBL-Targets; CHEMBL612655 PubChem_Cell_line; CVCL_0188 | ||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q5008075 | ||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0001098 | ||||||||||||||||||||||||||||||||
Gene expression databases | GEO; GSE30192
GEO; GSM915162 GEO; GSM915166 GEO; GSM915174 GEO; GSM915179 GEO; GSM915182 GEO; GSM915186 GEO; GSM915188 GEO; GSM918408 GEO; GSM918410 GEO; GSM918411 GEO; GSM918415 GEO; GSM918417 GEO; GSM918422 GEO; GSM1354755 | ||||||||||||||||||||||||||||||||
Metabolomic databases | MetaboLights; MTBLS127 | ||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD000022
PRIDE; PXD000288 PRIDE; PXD000328 PRIDE; PXD000589 PRIDE; PXD003211 PRIDE; PXD004151 PRIDE; PXD004960 PRIDE; PXD012986 PRIDE; PXD017465 PRIDE; PXD050867 PRIDE; PXD050903 | ||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||
Last entry update | 10-Apr-2025 | ||||||||||||||||||||||||||||||||
Version number | 39 |