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Cellosaurus C2C12-BRE (CVCL_B0JA)

[Text version]
Cell line name C2C12-BRE
Synonyms C2C12BRE; Clone 22
Accession CVCL_B0JA
Resource Identification Initiative To cite this cell line use: C2C12-BRE (RRID:CVCL_B0JA)
Comments Characteristics: Allows a sensitive, rapid and specific cell based assay for the simultaneous quantification of total and isoform specific BMP activity from biological samples (PubMed=19298647).
Characteristics: Transfected with a construct in which the luciferase reporter gene is under the control of the BMP responsive element (BRE) of the Id1 promoter region.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134.
Cell type: Myoblast; CL=CL_0000056.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Parent: CVCL_0188 (C2C12)
Sex of cell Female
Age at sampling 2M
Category Spontaneously immortalized cell line
Publications

PubMed=19298647; DOI=10.1186/1471-2121-10-20
Herrera B., Inman G.J.
A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum.
BMC Cell Biol. 10:20.1-20.11(2009)

Cross-references
Encyclopedic resources Wikidata; Q108819972
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number5