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Cellosaurus C2C12-Bmpr1b (CVCL_RQ02)

[Text version]
Cell line name C2C12-Bmpr1b
Accession CVCL_RQ02
Resource Identification Initiative To cite this cell line use: C2C12-Bmpr1b (RRID:CVCL_RQ02)
Comments Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1077; BMPR1B.
Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134.
Cell type: Myoblast; CL=CL_0000056.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Parent: CVCL_0188 (C2C12)
Sex of cell Female
Age at sampling 2M
Category Spontaneously immortalized cell line
Publications

PubMed=16957682; DOI=10.1038/sj.ejhg.5201708
Katarina Lehmann, Petra Seemann, Jan Boergermann, Gilles Morin, Silke Reif, Petra Knaus, Stefan Mundlos;
A novel R486Q mutation in BMPR1B resulting in either a brachydactyly type C/symphalangism-like phenotype or brachydactyly type A2.
Eur. J. Hum. Genet. 14:1248-1254(2006)

PubMed=19956691; DOI=10.1371/journal.pgen.1000747; PMCID=PMC2776984
Petra Seemann, Anja Brehm, Jana Konig, Carsten Reissner, Sigmar Stricker, Pia Kuss, Julia Haupt, Stephanie Renninger, Joachim Nickel, Walter Sebald, Jay C. Groppe ...Show all 20 authors... , Frank Ploger, Jens Pohl, Mareen Schmidt-von Kegler, Maria Walther, Ingmar Gassner, Cristina Rusu, Andreas R. Janecke, Katarina Dathe, Stefan Mundlos; Show fewer authors
Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN.
PLoS Genet. 5:e1000747.1-e1000747.11(2009)

Cross-references
Encyclopedic resources Wikidata; Q54808120
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number12