Cellosaurus cell line C2C12-hITGA11 (CVCL

Cellosaurus C2C12-hITGA11 (CVCL_A0NQ)

Cross-references
Cell line name	C2C12-hITGA11
Synonyms	C2C12-hualpha11; C2C12-alpha11+; C2C12-alpha11
Accession	CVCL_A0NQ
Resource Identification Initiative	To cite this cell line use: C2C12-hITGA11 (RRID:CVCL_A0NQ)
Comments	Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6136; ITGA11. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134. Cell type: Myoblast; CL=CL_0000056.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C3H.
Hierarchy	Parent: CVCL_0188 (C2C12)
Sex of cell	Female
Age at sampling	2M
Category	Spontaneously immortalized cell line
Publications	PubMed=11518510; DOI=10.1006/dbio.2001.0363 Carl-Fredrik Tiger, Francoise Fougerousse, Gunilla Grundstrom, Teet Velling, Elon Donald Gullberg; Alpha11beta1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal nonmuscle cells. Dev. Biol. 237:116-129(2001) PubMed=31159419; DOI=10.3390/cancers11060765; PMCID=PMC6627481 Cedric Zeltz, Jahedul Alam, Heng-Shuo Liu, Pugazendhi Murugan Erusappan, Heinz Hoschuetzky, Anders Molven, Himalaya Parajuli, Edna Cukierman, Daniela Elena Costea, Ning Lu, Elon Donald Gullberg; Alpha11beta1 integrin is induced in a subset of cancer-associated fibroblasts in desmoplastic tumor stroma and mediates in vitro cell migration. Cancers (Basel) 11:765.1-765.21(2019) Patent=US20210079099 Elon Donald Gullberg; Antibody against alpha-11 integrin and its use. Patent number US20210079099, 18-Mar-2021
Encyclopedic resources	Wikidata; Q108819973
Entry history
Entry creation	23-Sep-2021
Last entry update	14-Aug-2025
Version number	7