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Cellosaurus ARD (CVCL_XD83)

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Cell line name ARD
Synonyms ard-1
Accession CVCL_XD83
Resource Identification Initiative To cite this cell line use: ARD (RRID:CVCL_XD83)
Comments From: Epstein, Joshua; Myeloma and Transplantation Research Center, Arkansas Cancer Research Center; Little Rock; USA.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasma cell; CL=CL_0000786.
Sequence variations
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A5RY (ARD-EZH2i-R)CVCL_A5RZ (ARD-pUTX)
Originate from same individual CVCL_D523 ! ARP-1
CVCL_D569 ! CAG
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000681

Markers:
AmelogeninX
CSF1PO11,12
D2S133820,21
D3S135815,18
D5S81812,13
D6S104319
D7S82010,12
D8S117910,13
D12S39118.3,22
D13S3179,14
D16S53911,12
D18S5115
D19S43313,14
D21S1128,31.2
FGA18,19,24
Penta E7,15
TH016,7
TPOX11,12
vWA14,18

Run an STR similarity search on this cell line
Web pages Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines
Publications

PubMed=8427968; DOI=10.1182/blood.V81.3.767.767
Ronnie Cato Ridley, Hui-Qing Xiao, Hiroyuki Hata, Jeff Woodliff, Joshua Epstein, Ralph D. Sanderson;
Expression of syndecan regulates human myeloma plasma cell adhesion to type I collagen.
Blood 81:767-774(1993)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=14555701
Masood A. Shammas, Robert Joseph Shmookler Reis, Masaharu Akiyama, Hemanta Koley, Dharminder Chauhan, Teru Hideshima, Raj K. Goyal, Laurence H. Hurley, Kenneth Carl Anderson, Nikhil C. Munshi;
Telomerase inhibition and cell growth arrest by G-quadruplex interactive agent in multiple myeloma.
Mol. Cancer Ther. 2:825-833(2003)

PubMed=14760100; DOI=10.1158/1078-0432.CCR-0793-03
Masood A. Shammas, Robert Joseph Shmookler Reis, Cheng Li, Hemanta Koley, Laurence H. Hurley, Kenneth Carl Anderson, Nikhil C. Munshi;
Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma.
Clin. Cancer Res. 10:770-776(2004)

CLPUB00604
Sharon Chow;
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017); University of Toronto; Toronto; Canada

PubMed=29045832; DOI=10.1016/j.celrep.2017.09.078; PMCID=PMC5706555
Teresa Ezponda, Daphne Dupere-Richer, Christine M. Will, Eliza C. Small, Nobish Varghese, Tej Patel, Behnam Nabet, Relja Popovic, Jon Oyer, Marinka Bulic, Yu-Peng Zheng ...Show all 20 authors... , Xiao-Xiao Huang, Mrinal Y. Shah, Sayantan Maji, Alberto Riva, Manuela Occhionorelli, Giovanni Tonon, Neil L. Kelleher, Jonathan J. Keats, Jonathan D. Licht; Show fewer authors
UTX/KDM6A loss enhances the malignant phenotype of multiple myeloma and sensitizes cells to EZH2 inhibition.
Cell Rep. 21:628-640(2017)

Cross-references
Cell line databases/resources CCRID; 1101HUM-PUMC000681
Encyclopedic resources Wikidata; Q93325829
Gene expression databases GEO; GSM2774119
GEO; GSM2774122
GEO; GSM2774124
GEO; GSM2774126
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number12