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Cellosaurus ARP-1 (CVCL_D523)

[Text version]
Cell line name ARP-1
Synonyms ARP1; AR-P1; ARP
Accession CVCL_D523
Resource Identification Initiative To cite this cell line use: ARP-1 (RRID:CVCL_D523)
Comments Characteristics: Produces IgA kappa.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasma cell; CL=CL_0000786.
Sequence variations
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_XD83 ! ARD
CVCL_D569 ! CAG
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines
Publications

PubMed=7949178; DOI=10.1182/blood.V84.9.3063.3063
James Hardin, Stewart L. MacLeod, Irina Grigorieva, Rui-Xin Chang, Bart Barlogie, Hui-Qing Xiao, Joshua Epstein;
Interleukin-6 prevents dexamethasone-induced myeloma cell death.
Blood 84:3063-3070(1994)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=14555701
Masood A. Shammas, Robert Joseph Shmookler Reis, Masaharu Akiyama, Hemanta Koley, Dharminder Chauhan, Teru Hideshima, Raj K. Goyal, Laurence H. Hurley, Kenneth Carl Anderson, Nikhil C. Munshi;
Telomerase inhibition and cell growth arrest by G-quadruplex interactive agent in multiple myeloma.
Mol. Cancer Ther. 2:825-833(2003)

PubMed=14760100; DOI=10.1158/1078-0432.CCR-0793-03
Masood A. Shammas, Robert Joseph Shmookler Reis, Cheng Li, Hemanta Koley, Laurence H. Hurley, Kenneth Carl Anderson, Nikhil C. Munshi;
Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma.
Clin. Cancer Res. 10:770-776(2004)

PubMed=18647998; DOI=10.1093/jncimonographs/lgn011; PMCID=PMC2737184
Amel Dib, Ana Gabrea, Oleg K. Glebov, Peter Leif Bergsagel, Walter Michael Kuehl;
Characterization of MYC translocations in multiple myeloma cell lines.
J. Natl. Cancer Inst. Monogr. 39:25-31(2008)

CLPUB00604
Sharon Chow;
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017); University of Toronto; Toronto; Canada

PubMed=29045832; DOI=10.1016/j.celrep.2017.09.078; PMCID=PMC5706555
Teresa Ezponda, Daphne Dupere-Richer, Christine M. Will, Eliza C. Small, Nobish Varghese, Tej Patel, Behnam Nabet, Relja Popovic, Jon Oyer, Marinka Bulic, Yu-Peng Zheng ...Show all 20 authors... , Xiao-Xiao Huang, Mrinal Y. Shah, Sayantan Maji, Alberto Riva, Manuela Occhionorelli, Giovanni Tonon, Neil L. Kelleher, Jonathan J. Keats, Jonathan D. Licht; Show fewer authors
UTX/KDM6A loss enhances the malignant phenotype of multiple myeloma and sensitizes cells to EZH2 inhibition.
Cell Rep. 21:628-640(2017)

Cross-references
Anatomy/cell type resources BTO; BTO_0003931
Encyclopedic resources Wikidata; Q54750549
Experimental variables resources EFO; EFO_0022413
Gene expression databases GEO; GSM2774095
GEO; GSM2774097
GEO; GSM2774129
GEO; GSM2774131
GEO; GSM2774134
GEO; GSM2774136
Polymorphism and mutation databases Cosmic; 2367264
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number17