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Cellosaurus CAG (CVCL_D569)

[Text version]
Cell line name CAG
Accession CVCL_D569
Resource Identification Initiative To cite this cell line use: CAG (RRID:CVCL_D569)
Comments Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; 5722; IGKJ4 + HGNC; 5732; IGKV1-16; Name(s)=IGKV1-16-IGKJ4 (CelloPub=CLPUB00604).
  • Gene fusion; HGNC; 5723; IGKJ5 + HGNC; 5732; IGKV1-16; Name(s)=IGKV1-16-IGKJ5 (CelloPub=CLPUB00604).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_XD83 ! ARD
CVCL_D523 ! ARP-1
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Genomics_Center_BCF_Technion

Markers:
AmelogeninX
CSF1PO11,12
D1S165612,14
D2S4419,13
D2S133820
D3S135815,18
D5S81812,13
D7S82010,12
D8S117910,13
D10S124814
D12S39118.3,22
D13S3179
D16S53911,12
D18S5114,15
D19S43313,14
D21S1128,31.2
D22S104515
FGA19,24
Penta D13
Penta E7,15
TH016,7
TPOX11,12
vWA14,18

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Web pages https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
Publications

PubMed=11001907; DOI=10.1182/blood.V96.7.2528
Borset M., Hjertner O., Yaccoby S., Epstein J., Sanderson R.D.
Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparin-binding proteins.
Blood 96:2528-2536(2000)

CLPUB00604
Chow S.
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017), University of Toronto, Canada

Cross-references
Anatomy/cell type resources BTO; BTO:0005277
Encyclopedic resources Wikidata; Q54808368
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number9