ID   CAG
AC   CVCL_D569
DR   BTO; BTO:0005277
DR   Wikidata; Q54808368
RX   CelloPub=CLPUB00604;
RX   PubMed=11001907;
WW   https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
CC   Sequence variation: Gene fusion; HGNC; 5722; IGKJ4 + HGNC; 5732; IGKV1-16; Name(s)=IGKV1-16-IGKJ4 (CelloPub=CLPUB00604).
CC   Sequence variation: Gene fusion; HGNC; 5723; IGKJ5 + HGNC; 5732; IGKV1-16; Name(s)=IGKV1-16-IGKJ5 (CelloPub=CLPUB00604).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): Technion Genomics Center BCF
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D10S1248: 14
ST   D12S391: 18.3,22
ST   D13S317: 9
ST   D16S539: 11,12
ST   D18S51: 14,15
ST   D19S433: 13,14
ST   D1S1656: 12,14
ST   D21S11: 28,31.2
ST   D22S1045: 15
ST   D2S1338: 20
ST   D2S441: 9,13
ST   D3S1358: 15,18
ST   D5S818: 12,13
ST   D7S820: 10,12
ST   D8S1179: 10,13
ST   FGA: 19,24
ST   Penta D: 13
ST   Penta E: 7,15
ST   TH01: 6,7
ST   TPOX: 11,12
ST   vWA: 14,18
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_XD83 ! ARD
OI   CVCL_D523 ! ARP-1
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 02-05-24; Version: 10
//
RX   CelloPub=CLPUB00604;
RA   Chow S.;
RT   "Targeted capture and sequencing of immunoglobulin rearrangements
RT   in multiple myeloma to enable detection of minimal residual disease.";
RL   Thesis MSc (2017), University of Toronto, Canada.
//
RX   PubMed=11001907; DOI=10.1182/blood.V96.7.2528;
RA   Borset M., Hjertner O., Yaccoby S., Epstein J., Sanderson R.D.;
RT   "Syndecan-1 is targeted to the uropods of polarized myeloma cells
RT   where it promotes adhesion and sequesters heparin-binding proteins.";
RL   Blood 96:2528-2536(2000).
//