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Cellosaurus WM165-1 (CVCL_L033)

[Text version]
Cell line name WM165-1
Synonyms WM-165-1; WM 165-1
Accession CVCL_L033
Resource Identification Initiative To cite this cell line use: WM165-1 (RRID:CVCL_L033)
Comments Part of: Wistar Institute melanoma cell line collection.
Population: Caucasian.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Hemizygous (Wistar).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Asp (c.1799_1800delTGinsAT); ClinVar=VCV000375939; Zygosity=Heterozygous (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0040 ! WM115
CVCL_RN55 ! WM165-2
CVCL_6795 ! WM239A
CVCL_RN56 ! WM239B
CVCL_RN57 ! WM266-1
CVCL_RN58 ! WM266-2
CVCL_RN59 ! WM266-3
CVCL_2765 ! WM266-4
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO12
D2S133819
D3S135815,18
D5S81813
D7S8208
D8S117913,15
D13S31712
D16S53911,12
D18S5115,17
D19S43313
D21S1129
FGA21,23
TH017,9
TPOX8,11
vWA15,17

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Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=3856042; DOI=10.1093/jnci/74.2.283
Meenhard Herlyn, Gloria Brady Balaban-Malenbaum, Jeannette L. Bennicelli, DuPont Guerry 4th, Ruth Halaban, Dorothee Herlyn, David E. Elder, Gerd G. Maul, Zenon Steplewski, Peter Carey Nowell, Wallace H. Clark Jr., Hilary Koprowski;
Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.
J. Natl. Cancer Inst. 74:283-289(1985)

PubMed=4053039
Meenhard Herlyn, Jan Thurin, Gloria Brady Balaban-Malenbaum, Jeannette L. Bennicelli, Dorothee Herlyn, David E. Elder, Edward Bondi, DuPont Guerry 4th, Peter Carey Nowell, Wallace H. Clark Jr., Hilary Koprowski;
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer Res. 45:5670-5676(1985)

PubMed=2253310; DOI=10.1007/BF00046337
Meenhard Herlyn;
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

Cross-references
Cell line collections (Providers) Rockland; WM165-1-01-0001
Cell line databases/resources cancercelllines; CVCL_L033
Cell_Model_Passport; SIDM00977
Encyclopedic resources Wikidata; Q54994189
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number22