ID   WM165-1
AC   CVCL_L033
SY   WM-165-1; WM 165-1
DR   cancercelllines; CVCL_L033
DR   Cell_Model_Passport; SIDM00977
DR   Rockland; WM165-1-01-0001
DR   Wikidata; Q54994189
RX   PubMed=2253310;
RX   PubMed=3856042;
RX   PubMed=4053039;
CC   Part of: Wistar Institute melanoma cell line collection.
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 9588; PTEN; Zygosity=Hemizygous (Wistar).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Asp (c.1799_1800delTGinsAT); ClinVar=VCV000375939; Zygosity=Heterozygous (Wistar).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
ST   Source(s): Wistar
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 11,12
ST   D18S51: 15,17
ST   D19S433: 13
ST   D21S11: 29
ST   D2S1338: 19
ST   D3S1358: 15,18
ST   D5S818: 13
ST   D7S820: 8
ST   D8S1179: 13,15
ST   FGA: 21,23
ST   TH01: 7,9
ST   TPOX: 8,11
ST   vWA: 15,17
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_0040 ! WM115
OI   CVCL_RN55 ! WM165-2
OI   CVCL_6795 ! WM239A
OI   CVCL_RN56 ! WM239B
OI   CVCL_RN57 ! WM266-1
OI   CVCL_RN58 ! WM266-2
OI   CVCL_RN59 ! WM266-3
OI   CVCL_2765 ! WM266-4
SX   Female
AG   55Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 05-10-23; Version: 19
RX   PubMed=2253310; DOI=10.1007/BF00046337;
RA   Herlyn M.;
RT   "Human melanoma: development and progression.";
RL   Cancer Metastasis Rev. 9:101-112(1990).
RX   PubMed=3856042; DOI=10.1093/jnci/74.2.283;
RA   Herlyn M., Balaban G.B., Bennicelli J.L., Guerry D. IV, Halaban R.,
RA   Herlyn D., Elder D.E., Maul G.G., Steplewski Z., Nowell P.C.,
RA   Clark W.H. Jr., Koprowski H.;
RT   "Primary melanoma cells of the vertical growth phase: similarities to
RT   metastatic cells.";
RL   J. Natl. Cancer Inst. 74:283-289(1985).
RX   PubMed=4053039;
RA   Herlyn M., Thurin J., Balaban G.B., Bennicelli J.L., Herlyn D.,
RA   Elder D.E., Bondi E., Guerry D. IV, Nowell P.C., Clark W.H. Jr.,
RA   Koprowski H.;
RT   "Characteristics of cultured human melanocytes isolated from different
RT   stages of tumor progression.";
RL   Cancer Res. 45:5670-5676(1985).