ID   WM165-1
AC   CVCL_L033
SY   WM-165-1; WM 165-1
DR   cancercelllines; CVCL_L033
DR   Cell_Model_Passport; SIDM00977
DR   Rockland; WM165-1-01-0001
DR   Wikidata; Q54994189
RX   PubMed=2253310;
RX   PubMed=3856042;
RX   PubMed=4053039;
WW   Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
CC   Part of: Wistar Institute melanoma cell line collection.
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Hemizygous (Wistar).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Asp (c.1799_1800delTGinsAT); ClinVar=VCV000375939; Zygosity=Heterozygous (Wistar).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
ST   Source(s): Wistar
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 11,12
ST   D18S51: 15,17
ST   D19S433: 13
ST   D21S11: 29
ST   D2S1338: 19
ST   D3S1358: 15,18
ST   D5S818: 13
ST   D7S820: 8
ST   D8S1179: 13,15
ST   FGA: 21,23
ST   TH01: 7,9
ST   TPOX: 8,11
ST   vWA: 15,17
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_0040 ! WM115
OI   CVCL_RN55 ! WM165-2
OI   CVCL_6795 ! WM239A
OI   CVCL_RN56 ! WM239B
OI   CVCL_RN57 ! WM266-1
OI   CVCL_RN58 ! WM266-2
OI   CVCL_RN59 ! WM266-3
OI   CVCL_2765 ! WM266-4
SX   Female
AG   55Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 10-04-25; Version: 22
//
RX   PubMed=2253310; DOI=10.1007/BF00046337;
RA   Herlyn, Meenhard
RT   "Human melanoma: development and progression.";
RL   Cancer Metastasis Rev. 9:101-112(1990).
//
RX   PubMed=3856042; DOI=10.1093/jnci/74.2.283;
RA   Herlyn, Meenhard
RA   Balaban-Malenbaum, Gloria Brady
RA   Bennicelli, Jeannette L.
RA   Guerry, DuPont 4th
RA   Halaban, Ruth
RA   Herlyn, Dorothee
RA   Elder, David E.
RA   Maul, Gerd G.
RA   Steplewski, Zenon
RA   Nowell, Peter Carey
RA   Clark, Wallace H. Jr.
RA   Koprowski, Hilary
RT   "Primary melanoma cells of the vertical growth phase: similarities to
RT   metastatic cells.";
RL   J. Natl. Cancer Inst. 74:283-289(1985).
//
RX   PubMed=4053039;
RA   Herlyn, Meenhard
RA   Thurin, Jan
RA   Balaban-Malenbaum, Gloria Brady
RA   Bennicelli, Jeannette L.
RA   Herlyn, Dorothee
RA   Elder, David E.
RA   Bondi, Edward
RA   Guerry, DuPont 4th
RA   Nowell, Peter Carey
RA   Clark, Wallace H. Jr.
RA   Koprowski, Hilary
RT   "Characteristics of cultured human melanocytes isolated from different
RT   stages of tumor progression.";
RL   Cancer Res. 45:5670-5676(1985).
//