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Cellosaurus H357-V3 (CVCL_JY67)

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Cell line name H357-V3
Synonyms V3
Accession CVCL_JY67
Resource Identification Initiative To cite this cell line use: H357-V3 (RRID:CVCL_JY67)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6150; ITGAV.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Homozygous (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2462 (H357)
Children:
CVCL_JY68 (H357-VB6)
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
Publications

PubMed=8552382
Judith Jones, Masaru Sugiyama, Paul M. Speight, Fiona Mary Watt;
Restoration of alpha V beta 5 integrin expression in neoplastic keratinocytes results in increased capacity for terminal differentiation and suppression of anchorage-independent growth.
Oncogene 12:119-126(1996)

PubMed=11442751; DOI=10.1046/j.0022-202x.2001.01379.x
Gareth J. Thomas, Mark P. Lewis, Simon A. Whawell, Alan Russell, Dean Sheppard, Ian R. Hart, Paul M. Speight, John F. Marshall;
Expression of the alphavbeta6 integrin promotes migration and invasion in squamous carcinoma cells.
J. Invest. Dermatol. 117:67-73(2001)

Cross-references
Encyclopedic resources Wikidata; Q54992480
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number12