ID   H357-V3
AC   CVCL_JY67
SY   V3
DR   Wikidata; Q54992480
RX   PubMed=8552382;
RX   PubMed=11442751;
CC   Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6150; ITGAV.
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2462 ! H357
SX   Male
AG   74Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 19-12-24; Version: 12
CH   CVCL_JY68 ! H357-VB6
//
RX   PubMed=8552382;
RA   Jones, Judith
RA   Sugiyama, Masaru
RA   Speight, Paul M.
RA   Watt, Fiona Mary
RT   "Restoration of alpha V beta 5 integrin expression in neoplastic
RT   keratinocytes results in increased capacity for terminal
RT   differentiation and suppression of anchorage-independent growth.";
RL   Oncogene 12:119-126(1996).
//
RX   PubMed=11442751; DOI=10.1046/j.0022-202x.2001.01379.x;
RA   Thomas, Gareth J.
RA   Lewis, Mark P.
RA   Whawell, Simon A.
RA   Russell, Alan
RA   Sheppard, Dean
RA   Hart, Ian R.
RA   Speight, Paul M.
RA   Marshall, John F.
RT   "Expression of the alphavbeta6 integrin promotes migration and
RT   invasion in squamous carcinoma cells.";
RL   J. Invest. Dermatol. 117:67-73(2001).
//