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Cellosaurus H357 (CVCL_2462)

[Text version]
Cell line name H357
Accession CVCL_2462
Resource Identification Initiative To cite this cell line use: H357 (RRID:CVCL_2462)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Unspecified (DepMap=ACH-001509).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Homozygous (PubMed=7633286).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_JY67 (H357-V3)
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001509

Markers:
AmelogeninX,Y
CSF1PO11,13
D3S135817,18
D5S81812,14
D7S82011
D8S117913
D13S31712,13
D16S53911,12
D18S5114,17
D21S1129,31.2
FGA23,26
Penta D6,12
Penta E11,13
TH016,9
TPOX8,11
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=1692339; DOI=10.1002/path.1711600313
Stephen S. Prime, Sally V.R. Nixon, Isabel J. Crane, Andrea Stone, John B. Matthews, Norman J. Maitland, Lucy Remnant, Susan K. Powell, Stephen M. Game, Crispian Scully;
The behaviour of human oral squamous cell carcinoma in cell culture.
J. Pathol. 160:259-269(1990)

PubMed=7633286; DOI=10.1016/0964-1955(94)00030-8
William Andrew Yeudall, Ian C. Paterson, Vyomesh Patel, Stephen S. Prime;
Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53.
Eur. J. Cancer B. Oral Oncol. 31:136-143(1995)

PubMed=8552382
Judith Jones, Masaru Sugiyama, Paul M. Speight, Fiona Mary Watt;
Restoration of alpha V beta 5 integrin expression in neoplastic keratinocytes results in increased capacity for terminal differentiation and suppression of anchorage-independent growth.
Oncogene 12:119-126(1996)

PubMed=17944752; DOI=10.1111/j.1600-0714.2007.00617.x
Lisa J. Harper, Kim Piper, John E.A. Common, Farida Fortune, Ian C. Mackenzie;
Stem cell patterns in cell lines derived from head and neck squamous cell carcinoma.
J. Oral Pathol. Med. 36:594-603(2007)

PubMed=20426848; DOI=10.1186/1471-2407-10-166; PMCID=PMC2868812
Lisa J. Harper, Daniela Elena Costea, Luke Gammon, Bilal Fazil, Adrian Biddle, Ian C. Mackenzie;
Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance.
BMC Cancer 10:166.1-166.16(2010)

PubMed=27846777; DOI=10.1089/ten.TEC.2016.0310
Luke R. Jennings, Helen E. Colley, Jane Ong, Foti Panagakos, James G. Masters, Harsh M. Trivedi, Craig Murdoch, Simon A. Whawell;
Development and characterization of in vitro human oral mucosal equivalents derived from immortalized oral keratinocytes.
Tissue Eng. Part C. Methods 22:1108-1117(2016)

Cross-references
Cell line collections (Providers) CancerTools; 153422
ECACC; 06092004 - Discontinued
Ximbio; 153422
Cell line databases/resources Cell_Model_Passport; SIDM01810
DepMap; ACH-001509
Encyclopedic resources Wikidata; Q54872075
Polymorphism and mutation databases Cosmic; 716676
Cosmic; 916370
Cosmic; 928237
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21