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Cellosaurus 1181N1 (CVCL_D317)

[Text version]
Cell line name 1181N1
Synonyms 118MG-1181N1
Accession CVCL_D317
Resource Identification Initiative To cite this cell line use: 1181N1 (RRID:CVCL_D317)
Comments Problematic cell line: Contaminated. Parent cell line (U-118MG) has been shown to be a U-138MG derivative.
Population: Caucasian.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; c.1026+1G>T (IVS8+1G>T); ClinVar=VCV000635377; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Homozygous (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0633 (U-118MG)
CVCL_0110 (1321N1)CVCL_T435 (V-1181N1)
Sex of cell Male
Age at sampling 47Y
Category Cancer cell line

PubMed=4337530; DOI=10.1111/j.1699-0463.1972.tb02176.x
Macintyre E.H., Ponten J., Vatter A.E.
The ultrastructure of human and murine astrocytes and of human fibroblasts in culture.
Acta Pathol. Microbiol. Scand. A. 80:267-283(1972)

Cell line databases/resources cancercelllines; CVCL_D317
Cell_Model_Passport; SIDM01941
Encyclopedic resources Wikidata; Q54581030
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number20