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Cellosaurus MC-38 (CVCL_B288)

[Text version]

Cell line name MC-38
Synonyms MCA-38; MCA 38; MCA38; MC38; Mouse Colon 38; Murine Carcinoma-38; Colon 38; Colon-38; Colon38; C38
Accession CVCL_B288
Resource Identification Initiative To cite this cell line use: MC-38 (RRID:CVCL_B288)
Comments Omics: Mitochondrial genome sequenced.
Omics: SNP array analysis.
Caution: The authors of PubMed=25434994 indicate that they have sequenced the mitochondrial genome of the 'rat' cell line MCA38. Their submitted DNA sequence (KM820832.1) is indeed a rat sequence but is labelled as originating from 'rat isolate 406'.
Derived from sampling site: Colon.
Disease Mouse colon adenocarcinoma (NCIt: C120044)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_5I36 (MC-38-CEA-1 )CVCL_5I37 (MC-38-CEA-2 )CVCL_5I38 (MC-38-MUC-1 )
CVCL_XZ58 (MC38 human PDL1 )CVCL_B7NL (MC38-hPD-L1 )CVCL_B7NQ (MC38-Luc-RFP )
CVCL_B7NM (MC38-PD-L1 KO )CVCL_XJ96 (MC38-OVA )CVCL_0A68 (MC38/0 )
CVCL_0A67 (MC38Luc1 )CVCL_B9CM (MC38Luc4 )CVCL_B9CN (MC38Luc8 )
Sex of cell Female
Category Cancer cell line

Corbett T.H., Griswold D.P. Jr., Roberts B.J., Peckham J.C., Schabel F.M. Jr.
Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.
Cancer Res. 35:2434-2439(1975)

PubMed=1255804; DOI=10.1093/jnci/56.4.871
Tan M.H., Holyoke E.D., Goldrosen M.H.
Murine colon adenocarcinomas: methods for selective culture in vitro.
J. Natl. Cancer Inst. 56:871-873(1976)

PubMed=25277546; DOI=10.1186/1471-2164-15-847
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

PubMed=25434994; DOI=10.3109/19401736.2014.974176
Zhang C.-F., Yu X.-J., Wang B.-Y., Chen H.-W., Hu C.-E.
Whole mitochondrial genome sequence of a rat colorectal cancer MCA38 cell line.
Mitochondrial DNA 27:2034-2035(2016)

Cell line collections Kerafast; ENH204-FP
Cell line databases/resources CCRID; 1101MOU-PUMC000523
Lonza; 893
Anatomy/cell type resources BTO; BTO:0004163
Chemistry resources ChEMBL-Cells; CHEMBL3307696
ChEMBL-Targets; CHEMBL612821
Encyclopedic resources Wikidata; Q54904168
Entry history
Entry creation06-Jun-2012
Last entry update23-Jun-2022
Version number17