ID   MC-38
AC   CVCL_B288
SY   MCA-38; MCA 38; MCA38; MC38; Mouse Colon 38; Murine Carcinoma-38; Colon-38; Colon 38; Colon38; C38
DR   BTO; BTO_0004163
DR   ABM; T8291
DR   CCRID; 1101MOU-PUMC000523
DR   ChEMBL-Cells; CHEMBL3307696
DR   ChEMBL-Targets; CHEMBL612821
DR   CLS; 305223
DR   Kerafast; ENH204-FP
DR   Lonza; 893
DR   Millipore; SCC172
DR   PubChem_Cell_line; CVCL_B288
DR   Ubigene; YC-A002
DR   Wikidata; Q54904168
RX   PubMed=1149045;
RX   PubMed=1255804;
RX   PubMed=16320114;
RX   PubMed=25277546;
RX   PubMed=25434994;
WW   Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/colon-cancer-xenograft/mc38-xenograft-model/
CC   Doubling time: 24.3 hours (PubMed=16320114).
CC   Omics: Genomics; Mitochondrial genome sequencing.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Caution: The authors of PubMed=25434994 indicate that they have sequenced the mitochondrial genome of the 'rat' cell line MCA38. Their submitted DNA sequence (KM820832.1) is indeed a rat sequence but is labelled as originating from 'rat isolate 406'.
CC   Discontinued: CLS; 305223; true.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
CC   Breed/subspecies: C57BL/6.
ST   Source(s): Millipore=SCC172; Ubigene=YC-A002
ST   Mouse STR 1-1: 15,16,17
ST   Mouse STR 1-2: 18,19,20
ST   Mouse STR 2-1: 16
ST   Mouse STR 3-2: 14,15
ST   Mouse STR 4-2: 20.3
ST   Mouse STR 5-5: 16,17 (Ubigene=YC-A002)
ST   Mouse STR 5-5: 17 (Millipore=SCC172)
ST   Mouse STR 6-4: 17,18 (Millipore=SCC172)
ST   Mouse STR 6-4: 18 (Ubigene=YC-A002)
ST   Mouse STR 6-7: 15,16
ST   Mouse STR 7-1: 26.2
ST   Mouse STR 8-1: 16
ST   Mouse STR 11-2: 16
ST   Mouse STR 12-1: 16,17,18 (Millipore=SCC172)
ST   Mouse STR 12-1: 17 (Ubigene=YC-A002)
ST   Mouse STR 13-1: 17
ST   Mouse STR 15-3: 22.3 (Millipore=SCC172)
ST   Mouse STR 15-3: 22.3,23.3 (Ubigene=YC-A002)
ST   Mouse STR 17-2: 15,16
ST   Mouse STR 18-3: 15,16
ST   Mouse STR 19-2: 13
ST   Mouse STR X-1: 27
DI   NCIt; C120044; Mouse colon adenocarcinoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 25
//
RX   PubMed=1149045;
RA   Corbett T.H., Griswold D.P. Jr., Roberts B.J., Peckham J.C.,
RA   Schabel F.M. Jr.;
RT   "Tumor induction relationships in development of transplantable
RT   cancers of the colon in mice for chemotherapy assays, with a note on
RT   carcinogen structure.";
RL   Cancer Res. 35:2434-2439(1975).
//
RX   PubMed=1255804; DOI=10.1093/jnci/56.4.871;
RA   Tan M.H., Holyoke E.D., Goldrosen M.H.;
RT   "Murine colon adenocarcinomas: methods for selective culture in
RT   vitro.";
RL   J. Natl. Cancer Inst. 56:871-873(1976).
//
RX   PubMed=16320114; DOI=10.1007/s10585-005-3585-0;
RA   Morimoto-Tomita M., Ohashi Y., Matsubara A., Tsuiji M., Irimura T.;
RT   "Mouse colon carcinoma cells established for high incidence of
RT   experimental hepatic metastasis exhibit accelerated and
RT   anchorage-independent growth.";
RL   Clin. Exp. Metastasis 22:513-521(2005).
//
RX   PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738;
RA   Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W.,
RA   Morse H.C. 3rd, Pardo-Manuel de Villena F.;
RT   "SNP array profiling of mouse cell lines identifies their strains of
RT   origin and reveals cross-contamination and widespread aneuploidy.";
RL   BMC Genomics 15:847.1-847.11(2014).
//
RX   PubMed=25434994; DOI=10.3109/19401736.2014.974176;
RA   Zhang C.-F., Yu X.-J., Wang B.-Y., Chen H.-W., Hu C.-E.;
RT   "Whole mitochondrial genome sequence of a rat colorectal cancer MCA38
RT   cell line.";
RL   Mitochondrial DNA A. DNA Mapp. Seq. Anal. 27:2034-2035(2016).
//