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Cellosaurus MSU-1.1 (CVCL_9S81)

[Text version]
Cell line name MSU-1.1
Synonyms MSU1.1
Accession CVCL_9S81
Resource Identification Initiative To cite this cell line use: MSU-1.1 (RRID:CVCL_9S81)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P01110; Avian myelocytomatosis virus 29 v-Myc.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: v-Myc.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9S99 (MSU-1.0)
Children:
CVCL_9S82 (GM15916)CVCL_XG19 (MSU-1.1-N-ras 2)CVCL_XG20 (MSU-1.1-N-ras 3)
CVCL_XG21 (MSU-1.1-S41)CVCL_XG22 (MSU-1.1-S62)CVCL_XG25 (MSU-1.1-T24 2)
CVCL_XG26 (MSU-1.1-T24 3)CVCL_XG23 (MSU-1.1-v-Ki-ras 1)CVCL_XG24 (MSU-1.1-v-Ki-ras 2)
Sex of cell Male
Age at sampling <1M
Category Transformed cell line
Publications

PubMed=2643097; DOI=10.1073/pnas.86.1.187; PMCID=PMC286429
Peter J. Hurlin, Veronica M. Maher, J. Justin McCormick;
Malignant transformation of human fibroblasts caused by expression of a transfected T24 HRAS oncogene.
Proc. Natl. Acad. Sci. U.S.A. 86:187-191(1989)

DOI=10.1007/978-1-4612-0411-4_35
J. Justin McCormick, Veronica M. Maher;
Malignant transformation of human fibroblasts in vitro.
(In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim, Johng Sik & Dritschilo, Anatoly (eds.); pp.347-357; Humana Press; New York; USA (1990)

PubMed=2201439
Daniel M. Wilson, Da-Jun Yang, John E. Dillberger, Stephen E. Dietrich, Veronica M. Maher, J. Justin McCormick;
Malignant transformation of human fibroblasts by a transfected N-ras oncogene.
Cancer Res. 50:5587-5593(1990)

PubMed=2216465
Dennis G. Fry, Lonnie D. Milam, John E. Dillberger, Veronica M. Maher, J. Justin McCormick;
Malignant transformation of an infinite life span human fibroblast cell strain by transfection with v-Ki-ras.
Oncogene 5:1415-1418(1990)

PubMed=1915659; DOI=10.1016/0014-4827(91)90489-H
Thomas L. Morgan, Da-Jun Yang, Dennis G. Fry, Peter J. Hurlin, Suzanne K. Kohler, Veronica M. Maher, J. Justin McCormick;
Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfected v-myc oncogene.
Exp. Cell Res. 197:125-136(1991)

PubMed=9419347; DOI=10.1073/pnas.95.1.167; PMCID=PMC18162
Duncan J. Clarke, Juan F. Gimenez-Abian, Holger Tonnies, Heidemarie Neitzel, Karl Sperling, C. Stephen Downes, Robert T. Johnson;
Creation of monosomic derivatives of human cultured cell lines.
Proc. Natl. Acad. Sci. U.S.A. 95:167-171(1998)

PubMed=11888918
Pamela A. Havre, Sandra O'Reilly, J. Justin McCormick, Douglas E. Brash;
Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine.
Cancer Res. 62:1443-1449(2002)

PubMed=15705902
Zhen-Jun Lou, Sandra O'Reilly, Hong-Yan Liang, Veronica M. Maher, Stuart D. Sleight, J. Justin McCormick;
Down-regulation of overexpressed Sp1 protein in human fibrosarcoma cell lines inhibits tumor formation.
Cancer Res. 65:1007-1017(2005)

PubMed=18048363; DOI=10.1074/jbc.M709046200
Piro Lito, Bryan D. Mets, Susanne Kleff, Sandra O'Reilly, Veronica M. Maher, J. Justin McCormick;
Evidence that sprouty 2 is necessary for sarcoma formation by H-Ras oncogene-transformed human fibroblasts.
J. Biol. Chem. 283:2002-2009(2008)

PubMed=19008219; DOI=10.1074/jbc.M808045200; PMCID=PMC2613613
Piro Lito, Bryan D. Mets, Daniel M. Appledorn, Veronica M. Maher, J. Justin McCormick;
Sprouty 2 regulates DNA damage-induced apoptosis in Ras-transformed human fibroblasts.
J. Biol. Chem. 284:848-854(2009)

Cross-references
Encyclopedic resources Wikidata; Q54906902
Entry history
Entry creation23-Feb-2016
Last entry update14-Aug-2025
Version number11