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Cellosaurus MSU-1.1-N-ras 3 (CVCL_XG20)

[Text version]
Cell line name MSU-1.1-N-ras 3
Synonyms N-Ras-3T
Accession CVCL_XG20
Resource Identification Initiative To cite this cell line use: MSU-1.1-N-ras 3 (RRID:CVCL_XG20)
Comments Characteristics: Tumorigenic.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7989; NRAS.
Genetic integration: Method=Transfection; Gene=UniProtKB; P01110; Avian myelocytomatosis virus 29 v-Myc.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: v-Myc.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9S81 (MSU-1.1)
Sex of cell Male
Age at sampling <1M
Category Transformed cell line
Publications

PubMed=2201439
Daniel M. Wilson, Da-Jun Yang, John E. Dillberger, Stephen E. Dietrich, Veronica M. Maher, J. Justin McCormick;
Malignant transformation of human fibroblasts by a transfected N-ras oncogene.
Cancer Res. 50:5587-5593(1990)

PubMed=18048363; DOI=10.1074/jbc.M709046200
Piro Lito, Bryan D. Mets, Susanne Kleff, Sandra O'Reilly, Veronica M. Maher, J. Justin McCormick;
Evidence that sprouty 2 is necessary for sarcoma formation by H-Ras oncogene-transformed human fibroblasts.
J. Biol. Chem. 283:2002-2009(2008)

Cross-references
Encyclopedic resources Wikidata; Q95991328
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number8