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Cellosaurus MSU-1.0 (CVCL_9S99)

[Text version]
Cell line name MSU-1.0
Synonyms MSU 1.0; MSU1.0
Accession CVCL_9S99
Resource Identification Initiative To cite this cell line use: MSU-1.0 (RRID:CVCL_9S99)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P01110; Avian myelocytomatosis virus 29 v-Myc.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: v-Myc.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_XG18 (LG1)
Children:
CVCL_9S81 (MSU-1.1)
Sex of cell Male
Age at sampling <1M
Category Transformed cell line
Publications

DOI=10.1007/978-1-4612-0411-4_35
J. Justin McCormick, Veronica M. Maher;
Malignant transformation of human fibroblasts in vitro.
(In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim, Johng Sik & Dritschilo, Anatoly (eds.); pp.347-357; Humana Press; New York; USA (1990)

PubMed=1915659; DOI=10.1016/0014-4827(91)90489-H
Thomas L. Morgan, Da-Jun Yang, Dennis G. Fry, Peter J. Hurlin, Suzanne K. Kohler, Veronica M. Maher, J. Justin McCormick;
Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfected v-myc oncogene.
Exp. Cell Res. 197:125-136(1991)

PubMed=11888918
Pamela A. Havre, Sandra O'Reilly, J. Justin McCormick, Douglas E. Brash;
Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine.
Cancer Res. 62:1443-1449(2002)

PubMed=18048363; DOI=10.1074/jbc.M709046200
Piro Lito, Bryan D. Mets, Susanne Kleff, Sandra O'Reilly, Veronica M. Maher, J. Justin McCormick;
Evidence that sprouty 2 is necessary for sarcoma formation by H-Ras oncogene-transformed human fibroblasts.
J. Biol. Chem. 283:2002-2009(2008)

Cross-references
Cell line databases/resources TOKU-E; 4098
Encyclopedic resources Wikidata; Q54906901
Entry history
Entry creation23-Feb-2016
Last entry update14-Aug-2025
Version number12